Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2596398..2596666 Replicon chromosome
Accession NZ_CP027103
Organism Escherichia coli strain RM14723

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2596436..2596538 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2596398..2596666 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C5099_RS13485 2593555..2594994 + 1440 WP_001313925.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
C5099_RS13490 2595112..2595348 + 237 WP_001295499.1 DUF1480 family protein -
C5099_RS13495 2595453..2595644 + 192 WP_001357784.1 YebW family protein -
C5099_RS13500 2595645..2596301 - 657 WP_001357783.1 protein-serine/threonine phosphatase -
- 2596398..2596666 + 269 - - Antitoxin
- 2596436..2596538 - 103 - - Toxin
C5099_RS13505 2596696..2597037 - 342 WP_001357782.1 YebY family protein -
C5099_RS13510 2597050..2597922 - 873 WP_001357781.1 copper homeostasis membrane protein CopD -
C5099_RS13515 2597926..2598300 - 375 WP_000168747.1 CopC domain-containing protein YobA -
C5099_RS13520 2598439..2598669 + 231 WP_000916763.1 DNA polymerase III subunit theta -
C5099_RS13525 2598770..2599426 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
C5099_RS13530 2599450..2600112 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T97251 NZ_CP027103:c2596538-2596436 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT97251 NZ_CP027103:2596398-2596666 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References