Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2017164..2017309 | Replicon | chromosome |
| Accession | NZ_CP027048 | ||
| Organism | Klebsiella pneumoniae strain 20_GR_12 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2017200..2017302 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2017164..2017309 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A6D86_RS10110 | 2012294..2014354 | + | 2061 | WP_032422099.1 | oligopeptidase B | - |
| A6D86_RS10115 | 2014358..2015017 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| A6D86_RS10120 | 2015096..2015326 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| A6D86_RS10125 | 2015439..2015813 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| A6D86_RS10130 | 2015817..2016686 | + | 870 | WP_004151447.1 | copper homeostasis membrane protein CopD | - |
| A6D86_RS10135 | 2016703..2017041 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2017164..2017309 | - | 146 | - | - | Antitoxin |
| - | 2017200..2017302 | + | 103 | - | - | Toxin |
| A6D86_RS29140 | 2017677..2017820 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| A6D86_RS10145 | 2017925..2018893 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| A6D86_RS10150 | 2019050..2019703 | + | 654 | WP_002911396.1 | protein-serine/threonine phosphatase | - |
| A6D86_RS10155 | 2019700..2019891 | - | 192 | WP_002911395.1 | YebW family protein | - |
| A6D86_RS10160 | 2019989..2020228 | - | 240 | WP_002911393.1 | YebV family protein | - |
| A6D86_RS10165 | 2020344..2021777 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T97154 NZ_CP027048:2017200-2017302 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT97154 NZ_CP027048:c2017309-2017164 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
