Detailed information of TA system TA096860

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2066625..2066807
• Replicon: chromosome
• Accession: NZ_CP026961
• Organism: Staphylococcus aureus strain FDAARGOS_10

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: RK68_RS15310
• Protein ID: WP_001801861.1
• Coordinates: 2066712..2066807 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2066625..2066684 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RK68_RS11205	2065763..2066140	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
RK68_RS11210	2066334..2066510	+	177	Protein_2065	transposase	-
RK68_RS11215	2066488..2066589	-	102	WP_001791893.1	hypothetical protein	-
-	2066625..2066684	+	60	-	-	Antitoxin
RK68_RS15310	2066712..2066807	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
RK68_RS11225	2067010..2067153	+	144	WP_001549059.1	transposase	-
RK68_RS11235	2067757..2068140	+	384	WP_000070812.1	hypothetical protein	-
RK68_RS11240	2068151..2068327	+	177	WP_000375476.1	hypothetical protein	-
RK68_RS11245	2068329..2068514	+	186	WP_000809857.1	hypothetical protein	-
RK68_RS11250	2068628..2069269	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
RK68_RS11255	2069487..2070038	-	552	WP_000414205.1	hypothetical protein	-
RK68_RS11260	2070136..2070480	-	345	WP_000627551.1	DUF3969 family protein	-
RK68_RS11265	2070521..2071147	-	627	WP_000669046.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	2033536..2104248	70712

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T96860 WP_001801861.1 NZ_CP026961:c2066807-2066712 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T96860 NZ_CP026961:c2066807-2066712 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT96860 NZ_CP026961:2066625-2066684 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin