Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2095787..2096058 Replicon chromosome
Accession NZ_CP026929
Organism Escherichia coli strain CFS3246

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2095917..2096020 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2095787..2096058 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4962_RS10180 2092342..2093004 - 663 WP_000944256.1 exodeoxyribonuclease X -
C4962_RS10185 2093028..2093684 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C4962_RS10190 2093786..2094016 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C4962_RS10195 2094155..2094529 + 375 WP_000168747.1 CopC domain-containing protein YobA -
C4962_RS10200 2094533..2095405 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
C4962_RS10205 2095418..2095759 + 342 WP_000976476.1 YebY family protein -
- 2095787..2096058 - 272 - - Antitoxin
- 2095917..2096020 + 104 - - Toxin
C4962_RS10210 2096155..2096811 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
C4962_RS10215 2096812..2097003 - 192 WP_000457842.1 YebW family protein -
C4962_RS10220 2097108..2097344 - 237 WP_001295499.1 DUF1480 family protein -
C4962_RS10225 2097462..2098901 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T96629 NZ_CP026929:2095917-2096020 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT96629 NZ_CP026929:c2096058-2095787 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References