Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1638279..1638513 | Replicon | chromosome |
| Accession | NZ_CP026802 | ||
| Organism | Shigella sonnei strain ATCC 29930 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1638280..1638383 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1638279..1638513 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C1P89_RS08745 | 1634418..1634600 | + | 183 | Protein_1673 | host-nuclease inhibitor Gam family protein | - |
| C1P89_RS08750 | 1634606..1635703 | + | 1098 | WP_001173292.1 | AAA family ATPase | - |
| C1P89_RS08755 | 1635754..1635942 | + | 189 | WP_000276803.1 | DUF1187 family protein | - |
| - | 1635760..1635938 | - | 179 | NuclAT_2 | - | - |
| - | 1635760..1635938 | - | 179 | NuclAT_2 | - | - |
| - | 1635760..1635938 | - | 179 | NuclAT_2 | - | - |
| - | 1635760..1635938 | - | 179 | NuclAT_2 | - | - |
| C1P89_RS08760 | 1636049..1636309 | + | 261 | WP_077447296.1 | excisionase | - |
| C1P89_RS08765 | 1636338..1637035 | + | 698 | WP_229318984.1 | IS1-like element IS1A family transposase | - |
| C1P89_RS08770 | 1637072..1638148 | + | 1077 | WP_001189101.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 1638279..1638513 | + | 235 | - | - | Antitoxin |
| - | 1638280..1638383 | - | 104 | - | - | Toxin |
| C1P89_RS08775 | 1638541..1638882 | - | 342 | WP_000976476.1 | YebY family protein | - |
| C1P89_RS08780 | 1638895..1639767 | - | 873 | WP_000879296.1 | copper homeostasis membrane protein CopD | - |
| C1P89_RS08785 | 1639771..1640145 | - | 375 | WP_000168735.1 | CopC domain-containing protein YobA | - |
| C1P89_RS08790 | 1640284..1640514 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| C1P89_RS08795 | 1640616..1641272 | + | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein YobB | - |
| C1P89_RS08800 | 1641296..1641958 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 | 1623485..1651489 | 28004 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T96038 NZ_CP026802:c1638383-1638280 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT96038 NZ_CP026802:1638279-1638513 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
