Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2205241..2205475 | Replicon | chromosome |
| Accession | NZ_CP026765 | ||
| Organism | Shigella flexneri strain 04-3145 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2205242..2205345 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2205241..2205475 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C1P85_RS11755 | 2200776..2201048 | + | 273 | WP_001277358.1 | host-nuclease inhibitor Gam family protein | - |
| C1P85_RS11760 | 2201078..2202175 | + | 1098 | WP_128882124.1 | AAA family ATPase | - |
| C1P85_RS11765 | 2202226..2202414 | + | 189 | WP_000276807.1 | DUF1187 family protein | - |
| - | 2202232..2202410 | - | 179 | NuclAT_0 | - | - |
| - | 2202232..2202410 | - | 179 | NuclAT_0 | - | - |
| - | 2202232..2202410 | - | 179 | NuclAT_0 | - | - |
| - | 2202232..2202410 | - | 179 | NuclAT_0 | - | - |
| C1P85_RS11770 | 2202515..2203670 | + | 1156 | WP_134797305.1 | IS3-like element IS600 family transposase | - |
| C1P85_RS11775 | 2203787..2204068 | + | 282 | WP_005127484.1 | excisionase | - |
| C1P85_RS11780 | 2204034..2205110 | + | 1077 | Protein_2216 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2205241..2205475 | + | 235 | - | - | Antitoxin |
| - | 2205242..2205345 | - | 104 | - | - | Toxin |
| C1P85_RS11785 | 2205503..2205844 | - | 342 | WP_000976476.1 | YebY family protein | - |
| C1P85_RS11790 | 2205857..2206729 | - | 873 | Protein_2218 | copper homeostasis membrane protein CopD | - |
| C1P85_RS11795 | 2206733..2207107 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| C1P85_RS11800 | 2207246..2207476 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| C1P85_RS11805 | 2207578..2208234 | + | 657 | Protein_2221 | carbon-nitrogen hydrolase family protein YobB | - |
| C1P85_RS11810 | 2208258..2208920 | + | 663 | WP_000944270.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T95721 NZ_CP026765:c2205345-2205242 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT95721 NZ_CP026765:2205241-2205475 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
