Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2437453..2437637 Replicon chromosome
Accession NZ_CP026073
Organism Staphylococcus aureus strain FDAARGOS_42

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag RL00_RS12535 Protein ID WP_000482647.1
Coordinates 2437453..2437560 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2437577..2437637 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RL00_RS12510 2432825..2433298 + 474 WP_000456497.1 GyrI-like domain-containing protein -
RL00_RS12515 2433421..2434632 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
RL00_RS12520 2434814..2435473 - 660 WP_000831301.1 membrane protein -
RL00_RS12525 2435533..2436675 - 1143 WP_001176871.1 glycerate kinase -
RL00_RS12530 2436933..2437319 + 387 WP_000779360.1 flippase GtxA -
RL00_RS12535 2437453..2437560 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2437577..2437637 - 61 - - Antitoxin
RL00_RS12545 2438244..2440007 + 1764 WP_001064815.1 ABC transporter ATP-binding protein/permease -
RL00_RS12550 2440032..2441765 + 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
RL00_RS12560 2441996..2442163 + 168 WP_001793334.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T93152 WP_000482647.1 NZ_CP026073:2437453-2437560 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T93152 NZ_CP026073:2437453-2437560 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT93152 NZ_CP026073:c2437637-2437577 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References