Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 179358..179542 Replicon chromosome
Accession NZ_CP026067
Organism Staphylococcus aureus strain FDAARGOS_21

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag RK79_RS00970 Protein ID WP_000482647.1
Coordinates 179435..179542 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 179358..179418 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK79_RS00945 174812..174979 - 168 WP_031927726.1 hypothetical protein -
RK79_RS00955 175210..176943 - 1734 WP_000486497.1 ABC transporter ATP-binding protein/permease -
RK79_RS00960 176968..178731 - 1764 WP_031927727.1 ABC transporter ATP-binding protein/permease -
- 179358..179418 + 61 - - Antitoxin
RK79_RS00970 179435..179542 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
RK79_RS00975 179676..180062 - 387 WP_000779353.1 flippase GtxA -
RK79_RS00980 180330..181472 + 1143 WP_001176870.1 glycerate kinase -
RK79_RS00985 181532..182191 + 660 WP_047212947.1 membrane protein -
RK79_RS00990 182373..183584 + 1212 WP_001191927.1 multidrug effflux MFS transporter -
RK79_RS00995 183707..184180 - 474 WP_000456493.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T93033 WP_000482647.1 NZ_CP026067:c179542-179435 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T93033 NZ_CP026067:c179542-179435 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT93033 NZ_CP026067:179358-179418 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References