Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 549909..550093 Replicon chromosome
Accession NZ_CP026063
Organism Staphylococcus aureus strain FDAARGOS_14

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag RK72_RS03180 Protein ID WP_000482652.1
Coordinates 549986..550093 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 549909..549969 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK72_RS03155 545364..545531 - 168 Protein_572 hypothetical protein -
RK72_RS03165 545762..547495 - 1734 WP_000486487.1 ABC transporter ATP-binding protein/permease -
RK72_RS03170 547520..549283 - 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
- 549909..549969 + 61 - - Antitoxin
RK72_RS03180 549986..550093 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
RK72_RS03185 550227..550613 - 387 WP_000779360.1 flippase GtxA -
RK72_RS03190 550881..552023 + 1143 WP_001176863.1 glycerate kinase -
RK72_RS03195 552083..552742 + 660 WP_000831298.1 membrane protein -
RK72_RS03200 552924..554135 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
RK72_RS03205 554258..554731 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T92982 WP_000482652.1 NZ_CP026063:c550093-549986 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T92982 NZ_CP026063:c550093-549986 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT92982 NZ_CP026063:549909-549969 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References