Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 824925..825582 Replicon chromosome
Accession NZ_CP026047
Organism Raoultella planticola strain FDAARGOS_64

Toxin (Protein)


Gene name cptA Uniprot ID A0A2X2EG10
Locus tag MC50_RS03865 Protein ID WP_032690815.1
Coordinates 824925..825335 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A514ELX1
Locus tag MC50_RS03870 Protein ID WP_004867358.1
Coordinates 825316..825582 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MC50_RS03845 820846..822579 - 1734 WP_032696678.1 single-stranded-DNA-specific exonuclease RecJ -
MC50_RS03850 822585..823298 - 714 WP_032690818.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
MC50_RS03855 823321..824217 - 897 WP_032690817.1 site-specific tyrosine recombinase XerD -
MC50_RS03860 824396..824917 + 522 WP_032690816.1 flavodoxin FldB -
MC50_RS03865 824925..825335 - 411 WP_032690815.1 protein YgfX Toxin
MC50_RS03870 825316..825582 - 267 WP_004867358.1 FAD assembly factor SdhE Antitoxin
MC50_RS03875 825879..826862 + 984 WP_047663460.1 tRNA-modifying protein YgfZ -
MC50_RS03880 826972..827631 - 660 WP_004867362.1 hemolysin III family protein -
MC50_RS03885 827793..828104 - 312 WP_004867365.1 N(4)-acetylcytidine aminohydrolase -
MC50_RS03890 828154..828882 + 729 WP_032690813.1 MurR/RpiR family transcriptional regulator -
MC50_RS03895 829002..830435 + 1434 WP_032690812.1 6-phospho-beta-glucosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16198.10 Da        Isoelectric Point: 11.3349

>T92922 WP_032690815.1 NZ_CP026047:c825335-824925 [Raoultella planticola]
VVLWQSDLRISWRSQWFSLLLHGIVAAIVLLMPWPLSYTPLWLLLLSLVVFDSVRSQRRIHACRGEIKLMTDSRLRWQKA
EWEIVGTPWVINSGMLLRLQDMQTRRRQHLWVAADSMDAKEWRDLRRLVLQKPAQD

Download         Length: 411 bp

>T92922 NZ_CP026047:c825335-824925 [Raoultella planticola]
GTGGTCCTGTGGCAATCTGATTTACGCATTTCCTGGCGCTCGCAGTGGTTCTCGCTGCTGCTGCACGGCATTGTGGCGGC
TATTGTCCTGCTGATGCCCTGGCCGCTGAGCTACACACCGCTATGGCTATTGCTGCTGTCGCTGGTGGTGTTCGACAGCG
TGCGCAGCCAGCGGCGGATCCACGCCTGCCGGGGGGAAATAAAGCTGATGACCGATTCGCGTTTGCGTTGGCAAAAAGCG
GAATGGGAAATTGTCGGCACGCCGTGGGTGATTAATAGCGGGATGTTGCTGCGCCTGCAGGATATGCAAACGCGTCGCCG
CCAGCATCTGTGGGTCGCTGCAGACAGTATGGATGCCAAAGAGTGGCGAGATCTGCGCCGGTTGGTTTTACAAAAACCGG
CACAGGATTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10553.05 Da        Isoelectric Point: 4.8432

>AT92922 WP_004867358.1 NZ_CP026047:c825582-825316 [Raoultella planticola]
MDITNKARIHWACRRGMRELDISIMPFFEYEYDTLSDEDKQLFIRLLENDDPDLFNWLMNHGEPADAQLQRMVKLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT92922 NZ_CP026047:c825582-825316 [Raoultella planticola]
ATGGACATTACGAATAAAGCCCGCATCCACTGGGCATGCCGCAGGGGTATGCGTGAACTTGATATCTCCATCATGCCGTT
TTTCGAGTATGAATACGATACGCTCAGCGATGAAGACAAACAGCTGTTTATCCGTCTGTTAGAAAACGACGATCCGGACC
TGTTTAACTGGCTGATGAATCATGGCGAACCGGCTGATGCACAACTGCAACGGATGGTAAAATTAATCCAGACTCGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2X2EG10

Antitoxin

Source ID Structure
AlphaFold DB A0A514ELX1

References