Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2083097..2083242 Replicon chromosome
Accession NZ_CP026023
Organism Klebsiella pneumoniae strain 11420

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2083133..2083235 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2083097..2083242 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2D59_RS09925 2078227..2080287 + 2061 WP_004151449.1 oligopeptidase B -
C2D59_RS09930 2080291..2080950 - 660 WP_002911407.1 exodeoxyribonuclease X -
C2D59_RS09935 2081029..2081259 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C2D59_RS09940 2081372..2081746 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C2D59_RS09945 2081750..2082619 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
C2D59_RS09950 2082636..2082974 + 339 WP_002911404.1 YebY family protein -
- 2083097..2083242 - 146 - - Antitoxin
- 2083133..2083235 + 103 - - Toxin
C2D59_RS09955 2083610..2083753 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C2D59_RS09960 2083858..2084826 - 969 WP_014907334.1 VirK/YbjX family protein -
C2D59_RS09965 2084983..2085636 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
C2D59_RS09970 2085633..2085824 - 192 WP_002911395.1 YebW family protein -
C2D59_RS09975 2085922..2086161 - 240 WP_002911393.1 YebV family protein -
C2D59_RS09980 2086277..2087710 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T92735 NZ_CP026023:2083133-2083235 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT92735 NZ_CP026023:c2083242-2083097 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References