Detailed information of TA system TA091987

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 2028890..2029559
• Replicon: chromosome
• Accession: NZ_CP025800
• Organism: Yersinia ruckeri strain SC09

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: A0A380QS17
• Locus tag: NJ56_RS09310
• Protein ID: WP_038241020.1
• Coordinates: 2029137..2029559 (+)
• Length: 141 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: NJ56_RS09305
• Protein ID: WP_004719196.1
• Coordinates: 2028890..2029156 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NJ56_RS09290	2026083..2026483	-	401	Protein_1758	HD domain-containing protein	-
NJ56_RS09295	2026800..2027465	+	666	WP_175537887.1	hemolysin III family protein	-
NJ56_RS09300	2027604..2028596	-	993	WP_038276203.1	tRNA-modifying protein YgfZ	-
NJ56_RS09305	2028890..2029156	+	267	WP_004719196.1	FAD assembly factor SdhE	Antitoxin
NJ56_RS09310	2029137..2029559	+	423	WP_038241020.1	protein YgfX	Toxin
NJ56_RS09315	2029707..2030225	-	519	WP_038241022.1	flavodoxin FldB	-
NJ56_RS09320	2030333..2031232	+	900	WP_004719193.1	site-specific tyrosine recombinase XerD	-
NJ56_RS09325	2031264..2031980	+	717	WP_038276201.1	bifunctional protein-disulfide isomerase/oxidoreductase DsbC	-
NJ56_RS09330	2031987..2033720	+	1734	WP_038276198.1	single-stranded-DNA-specific exonuclease RecJ	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (2-132)

Antitoxin

• Flavinator of succinate dehydrogenase (7-79)

Sequences

Toxin

Protein

• Length: 141 a.a.
• Molecular weight: 16451.41 Da
• Isoelectric Point: 11.1478

>T91987 WP_038241020.1 NZ_CP025800:2029137-2029559 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGAGSRRRKRIWLASDSMSEEKWRELCLILRHTFDSAAGRE

Nucleotide

• Length: 423 bp

>T91987 NZ_CP025800:2029137-2029559 [Yersinia ruckeri]
GTGGCCCAGTGGCGATGTGATCTGCGGGTTTCATGGCGCACCCAACTTTTCTCACTATTGGTACACGGTGTTCTGGTATT
ACTGACACTGGTGGTACCTTGGCCTGACGGATTTACTCCGCTATGGCTTATATTGCTGACGCTGGTGGTGTTTGAATGCA
TTCGCAGCCAGAAGAACATTACCTCTCGACAGGGAGAGATCCGGCTTAAAGCGGGAAATCTGTTGATTTGGAAGTGGCAA
GAGTGGACGTTGGTGCGGCCGCCGTGGATTACCCGCTACGGCGTATTATTATCGTTACAAGGCGCTGGCAGCCGCCGCCG
AAAACGTATTTGGCTAGCCTCCGACAGCATGTCGGAAGAAAAATGGCGCGAGTTGTGTCTGATATTACGACATACTTTTG
ATTCTGCGGCAGGCCGTGAGTAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10532.09 Da
• Isoelectric Point: 6.7185

>AT91987 WP_004719196.1 NZ_CP025800:2028890-2029156 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Nucleotide

• Length: 267 bp

>AT91987 NZ_CP025800:2028890-2029156 [Yersinia ruckeri]
ATGGAAATTGATAACAAAGCCCGAATCCATTGGGCATGCCGCCGGGGTATGCGTGAACTGGATATCTCCATAATGCCATT
TTTCGAACATGAATATGACACGCTAAACGATAATGATAAGCGCGTATTTATCCGCTTGCTGACGAGTGATGATCCTGATT
TATTCAATTGGTTGATGAACCACGGCGAGCCGCAGGATAGCGAACTGAAACGAATGGTTAAACTGATTCAGACACGAAAT
AAAGCCCGTGGCCCAGTGGCGATGTGA

Structures

Toxin

• AlphaFold DB: A0A380QS17