Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2034230..2034375 Replicon chromosome
Accession NZ_CP025080
Organism Klebsiella pneumoniae strain SGH10

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2034266..2034368 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2034230..2034375 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SGH10_RS09950 2029360..2031420 + 2061 WP_004151449.1 oligopeptidase B -
SGH10_RS09955 2031424..2032083 - 660 WP_002911407.1 exodeoxyribonuclease X -
SGH10_RS09960 2032162..2032392 - 231 WP_002911406.1 DNA polymerase III subunit theta -
SGH10_RS09965 2032505..2032879 + 375 WP_004151448.1 CopC domain-containing protein YobA -
SGH10_RS09970 2032883..2033752 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
SGH10_RS09975 2033769..2034107 + 339 WP_002911404.1 YebY family protein -
- 2034230..2034375 - 146 - - Antitoxin
- 2034266..2034368 + 103 - - Toxin
SGH10_RS28545 2034743..2034886 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
SGH10_RS09985 2034991..2035959 - 969 WP_014907334.1 VirK/YbjX family protein -
SGH10_RS09990 2036116..2036769 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
SGH10_RS09995 2036766..2036957 - 192 WP_002911395.1 YebW family protein -
SGH10_RS10000 2037055..2037294 - 240 WP_002911393.1 YebV family protein -
SGH10_RS10005 2037410..2038843 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T89738 NZ_CP025080:2034266-2034368 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT89738 NZ_CP025080:c2034375-2034230 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References