Detailed information of TA system TA088834

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ralRA/-
• Location: 3267176..3267547
• Replicon: chromosome
• Accession: NZ_CP024851
• Organism: Escherichia coli strain AR_0006

Toxin (Protein)

• Gene name: ralR
• Uniprot ID: A0A0D6ZRD3
• Locus tag: AM333_RS16850
• Protein ID: WP_001443846.1
• Coordinates: 3267398..3267547 (-)
• Length: 50 a.a.

Antitoxin (RNA)

Gene name	ralA
Locus tag	-
Coordinates	3267176..3267354 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AM333_RS16825	3263131..3264504	+	1374	WP_000123748.1	ATP-dependent RNA helicase DbpA	-
AM333_RS16830	3264633..3265568	-	936	WP_001523172.1	tRNA 2-thiocytidine(32) synthetase TtcA	-
AM333_RS16835	3265620..3266855	-	1236	WP_000040839.1	site-specific integrase	-
AM333_RS16840	3266857..3267072	-	216	WP_000079604.1	excisionase XisR	-
AM333_RS16845	3267172..3267360	-	189	WP_001302840.1	DUF1187 family protein	-
-	3267176..3267354	+	179	NuclAT_0	-	Antitoxin
-	3267176..3267354	+	179	NuclAT_0	-	Antitoxin
-	3267176..3267354	+	179	NuclAT_0	-	Antitoxin
-	3267176..3267354	+	179	NuclAT_0	-	Antitoxin
AM333_RS16850	3267398..3267547	-	150	WP_001443846.1	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	Toxin
AM333_RS16855	3267603..3268412	-	810	WP_000166313.1	recombination protein RecT	-
AM333_RS16860	3268405..3271005	-	2601	WP_000105140.1	exodeoxyribonuclease VIII	-
AM333_RS16865	3271107..3271382	-	276	WP_001344816.1	hypothetical protein	-
AM333_RS16870	3271457..3271627	-	171	WP_001352098.1	conserved protein, Rac prophage	-
AM333_RS16875	3271627..3271848	-	222	WP_000560223.1	killing protein KilR	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	3265620..3312621	47001

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Endodeoxyribonuclease toxin RalR (6-48)

Sequences

Toxin

Protein

• Length: 50 a.a.
• Molecular weight: 5383.12 Da
• Isoelectric Point: 8.3398

>T88834 WP_001443846.1 NZ_CP024851:c3267547-3267398 [Escherichia coli]
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALER

Nucleotide

• Length: 150 bp

>T88834 NZ_CP024851:c3267547-3267398 [Escherichia coli]
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAACGATGA

Antitoxin

Nucleotide

• Length: 179 bp

>AT88834 NZ_CP024851:3267176-3267354 [Escherichia coli]
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT

Structures

Toxin

• AlphaFold DB: A0A0D6ZRD3

Antitoxin