Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1977020..1977165 Replicon chromosome
Accession NZ_CP024545
Organism Klebsiella pneumoniae strain INF059

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1977056..1977158 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1977020..1977165 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTI65_RS09975 1972150..1974210 + 2061 WP_099728950.1 oligopeptidase B -
CTI65_RS09980 1974214..1974873 - 660 WP_002911407.1 exodeoxyribonuclease X -
CTI65_RS09985 1974952..1975182 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CTI65_RS09990 1975295..1975669 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CTI65_RS09995 1975673..1976542 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
CTI65_RS10000 1976559..1976897 + 339 WP_002911404.1 YebY family protein -
- 1977020..1977165 - 146 - - Antitoxin
- 1977056..1977158 + 103 - - Toxin
CTI65_RS28180 1977533..1977676 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CTI65_RS10010 1977781..1978749 - 969 WP_004151446.1 VirK/YbjX family protein -
CTI65_RS10015 1978906..1979559 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
CTI65_RS10020 1979556..1979747 - 192 WP_002911395.1 YebW family protein -
CTI65_RS10025 1979845..1980084 - 240 WP_002911393.1 YebV family protein -
CTI65_RS10030 1980200..1981633 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T87918 NZ_CP024545:1977056-1977158 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT87918 NZ_CP024545:c1977165-1977020 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References