Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 1196003..1196562 Replicon chromosome
Accession NZ_CP024311
Organism Rhizobium sp. NXC24

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NXC24_RS05960 Protein ID WP_104822466.1
Coordinates 1196003..1196368 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NXC24_RS05965 Protein ID WP_104822467.1
Coordinates 1196365..1196562 (-) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXC24_RS05940 1191039..1192283 - 1245 WP_104822464.1 efflux RND transporter periplasmic adaptor subunit -
NXC24_RS05945 1192715..1193504 - 790 Protein_1166 SDR family oxidoreductase -
NXC24_RS05950 1193790..1195454 + 1665 WP_104822465.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
NXC24_RS05955 1195460..1195987 + 528 WP_104825033.1 GNAT family N-acetyltransferase -
NXC24_RS05960 1196003..1196368 - 366 WP_104822466.1 PIN domain-containing protein Toxin
NXC24_RS05965 1196365..1196562 - 198 WP_104822467.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NXC24_RS05970 1196665..1197567 - 903 WP_104822468.1 DMT family transporter -
NXC24_RS05975 1197713..1198186 + 474 WP_104822469.1 Lrp/AsnC family transcriptional regulator -
NXC24_RS05980 1198237..1199610 - 1374 WP_104822470.1 magnesium transporter -
NXC24_RS35035 1199809..1199997 - 189 WP_158704428.1 hypothetical protein -
NXC24_RS05985 1200008..1201225 - 1218 WP_104822471.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-113)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-47)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13818.11 Da        Isoelectric Point: 8.4792

>T87606 WP_104822466.1 NZ_CP024311:c1196368-1196003 [Rhizobium sp. NXC24]
MILVDTSIWIDHFHSLDAKLQSLLEQKQVLIHPFVIGEISLGNLRQYDLVMRSLSRLYQISKAPDDDVLYFIRSNRLQGM
GIGYVDAHLAAAAILTPGTYLWTRDKRLQRVAENLRIAALL

Download         Length: 366 bp

>T87606 NZ_CP024311:c1196368-1196003 [Rhizobium sp. NXC24]
ATGATCTTGGTCGATACGTCGATTTGGATCGATCATTTTCATTCGCTGGACGCTAAACTTCAGTCTTTATTGGAGCAGAA
ACAGGTTCTCATCCATCCCTTCGTGATCGGTGAGATCAGCCTCGGAAACCTGAGGCAATATGATCTTGTTATGAGAAGTC
TGAGCCGGTTGTATCAGATTTCAAAGGCGCCAGATGATGACGTTCTTTATTTTATCCGGAGCAATAGATTACAAGGTATG
GGCATTGGCTATGTCGATGCTCACCTGGCGGCGGCGGCAATATTGACACCTGGCACCTATCTCTGGACGCGCGACAAGCG
GCTACAGCGCGTTGCCGAAAATCTCAGGATTGCCGCGTTGTTGTAG

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7174.25 Da        Isoelectric Point: 5.0959

>AT87606 WP_104822467.1 NZ_CP024311:c1196562-1196365 [Rhizobium sp. NXC24]
MRTTVTIDDKLLADAREVTELAETSAIVREALKALIEREAARTLIRLGGTEPDIAAPPRRRFGVE

Download         Length: 198 bp

>AT87606 NZ_CP024311:c1196562-1196365 [Rhizobium sp. NXC24]
ATGCGGACCACAGTAACCATTGATGACAAATTGCTCGCGGATGCGCGCGAAGTCACGGAATTGGCTGAGACCTCAGCGAT
CGTGCGCGAGGCGTTGAAAGCGCTTATCGAGCGAGAAGCTGCCAGAACGCTTATACGCCTTGGCGGCACGGAACCAGATA
TTGCGGCCCCTCCTCGTCGTCGGTTTGGTGTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References