Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2093975..2094246 Replicon chromosome
Accession NZ_CP024131
Organism Escherichia coli strain 14EC007

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2094105..2094208 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2093975..2094246 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CR535_RS11080 2090530..2091192 - 663 WP_000944256.1 exodeoxyribonuclease X -
CR535_RS11085 2091216..2091872 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
CR535_RS11090 2091974..2092204 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CR535_RS11095 2092343..2092717 + 375 WP_000168736.1 CopC domain-containing protein YobA -
CR535_RS11100 2092721..2093593 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
CR535_RS11105 2093606..2093947 + 342 WP_000976472.1 YebY family protein -
- 2093975..2094246 - 272 - - Antitoxin
- 2094105..2094208 + 104 - - Toxin
CR535_RS11110 2094343..2094999 + 657 WP_000812739.1 protein-serine/threonine phosphatase -
CR535_RS11115 2095000..2095191 - 192 WP_001313035.1 YebW family protein -
CR535_RS11120 2095296..2095532 - 237 WP_001295499.1 DUF1480 family protein -
CR535_RS11125 2095650..2097089 - 1440 WP_001383086.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T86812 NZ_CP024131:2094105-2094208 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT86812 NZ_CP024131:c2094246-2093975 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References