Detailed information of TA system TA086506

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): yeeV-yfjZ/CbtA-CbeA
• Location: 4803369..4804069
• Replicon: chromosome
• Accession: NZ_CP023962
• Organism: Yersinia frederiksenii strain FDAARGOS_417

Toxin (Protein)

• Gene name: yeeV
• Uniprot ID: -
• Locus tag: CRN74_RS22340
• Protein ID: WP_098905178.1
• Coordinates: 4803369..4803740 (+)
• Length: 124 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: CRN74_RS22345
• Protein ID: WP_098905179.1
• Coordinates: 4803737..4804069 (+)
• Length: 111 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CRN74_RS22315	4799195..4799632	+	438	WP_050082355.1	hypothetical protein	-
CRN74_RS22320	4799652..4800920	+	1269	WP_098905175.1	hypothetical protein	-
CRN74_RS22325	4801143..4801589	+	447	WP_050082359.1	hypothetical protein	-
CRN74_RS22330	4801664..4802485	+	822	WP_098905176.1	DUF945 domain-containing protein	-
CRN74_RS22335	4802846..4803277	+	432	WP_098905177.1	antirestriction protein	-
CRN74_RS22340	4803369..4803740	+	372	WP_098905178.1	TA system toxin CbtA family protein	Toxin
CRN74_RS22345	4803737..4804069	+	333	WP_098905179.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
CRN74_RS22350	4804154..4805014	+	861	WP_098905180.1	DUF4942 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (13-101)

Antitoxin

• Antitoxin CbeA (9-108)

Sequences

Toxin

Protein

• Length: 124 a.a.
• Molecular weight: 13624.67 Da
• Isoelectric Point: 6.8773

>T86506 WP_098905178.1 NZ_CP023962:4803369-4803740 [Yersinia frederiksenii]
MKPNPTTAGALPVPVIYQQLLAFLLEHHYGLSLNDTPYHDEQVIAQQIEQGISVGDTINTLVEKYALVRIGRNGFSALAQ
DPMLSKGDIVRARQAVGLWRAHFPPTLLYPTESLNPIPQRPLT

Nucleotide

• Length: 372 bp

>T86506 NZ_CP023962:4803369-4803740 [Yersinia frederiksenii]
ATGAAACCAAACCCCACAACAGCGGGTGCATTACCCGTGCCTGTTATTTATCAACAACTGCTCGCTTTCCTGCTGGAGCA
CCACTACGGCCTGAGCCTCAACGATACGCCCTATCACGATGAACAGGTGATTGCGCAACAGATAGAACAAGGGATTTCAG
TCGGCGACACCATCAACACACTGGTTGAGAAATATGCATTAGTGCGAATTGGTCGTAACGGGTTCAGCGCACTGGCGCAA
GACCCGATGTTGAGCAAGGGCGATATCGTGCGGGCTCGCCAGGCTGTTGGCCTGTGGCGGGCTCATTTCCCGCCCACATT
GCTGTACCCAACCGAATCCCTCAATCCTATTCCACAGAGACCGTTAACATGA

Antitoxin

Protein

• Length: 111 a.a.
• Molecular weight: 12091.72 Da
• Isoelectric Point: 6.9660

>AT86506 WP_098905179.1 NZ_CP023962:4803737-4804069 [Yersinia frederiksenii]
MNNHITTSPTWGLKRDITPRLGARLVQEGTHLHFLSDRANIAGTFSLEATQALDAAFPALITKLESQLLSGQLDPRRQQC
LTVRHGGFVCEADTLGSHGYVYIAVYQELA

Nucleotide

• Length: 333 bp

>AT86506 NZ_CP023962:4803737-4804069 [Yersinia frederiksenii]
ATGAATAACCACATTACTACTTCCCCAACATGGGGCCTGAAACGTGATATTACGCCGCGGTTGGGGGCCCGACTGGTACA
GGAGGGAACACACCTGCATTTTCTGAGCGACAGAGCCAACATAGCGGGTACCTTTTCCCTTGAAGCCACTCAGGCTCTTG
ATGCAGCGTTTCCCGCGCTGATAACCAAACTGGAATCGCAGTTGCTGTCCGGTCAGCTTGACCCTCGCCGTCAGCAGTGT
CTTACGGTCCGGCACGGGGGATTTGTCTGTGAAGCGGATACGCTGGGCAGTCACGGTTATGTCTACATCGCGGTGTATCA
GGAACTGGCTTGA