Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2136762..2137033 Replicon chromosome
Accession NZ_CP023673
Organism Escherichia coli strain SMN013SH2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2136892..2136995 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2136762..2137033 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CP957_RS11735 2133317..2133979 - 663 WP_000944256.1 exodeoxyribonuclease X -
CP957_RS11740 2134003..2134659 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
CP957_RS11745 2134761..2134991 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CP957_RS11750 2135130..2135504 + 375 WP_000168747.1 CopC domain-containing protein YobA -
CP957_RS11755 2135508..2136380 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
CP957_RS11760 2136393..2136734 + 342 WP_000976472.1 YebY family protein -
- 2136762..2137033 - 272 - - Antitoxin
- 2136892..2136995 + 104 - - Toxin
CP957_RS11765 2137130..2137786 + 657 WP_000812722.1 protein-serine/threonine phosphatase -
CP957_RS11770 2137787..2137978 - 192 WP_001296140.1 YebW family protein -
CP957_RS11775 2138083..2138319 - 237 WP_001295499.1 DUF1480 family protein -
CP957_RS11780 2138437..2139876 - 1440 WP_024226338.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T85870 NZ_CP023673:2136892-2136995 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT85870 NZ_CP023673:c2137033-2136762 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References