Detailed information of TA system TA085820

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 1417345..1418255
• Replicon: chromosome
• Accession: NZ_CP023656
• Organism: Halomonas hydrothermalis strain Y2

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: CLM76_RS06710
• Protein ID: WP_096921852.1
• Coordinates: 1417345..1417809 (-)
• Length: 155 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: CLM76_RS06715
• Protein ID: WP_039178599.1
• Coordinates: 1417806..1418255 (-)
• Length: 150 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CLM76_RS06690	1413032..1414639	+	1608	WP_039178610.1	urea ABC transporter permease subunit UrtB	-
CLM76_RS06695	1414646..1415788	+	1143	WP_096921850.1	urea ABC transporter permease subunit UrtC	-
CLM76_RS06700	1415785..1416621	+	837	WP_016915368.1	urea ABC transporter ATP-binding protein UrtD	-
CLM76_RS06705	1416621..1417328	+	708	WP_096921851.1	urea ABC transporter ATP-binding subunit UrtE	-
CLM76_RS06710	1417345..1417809	-	465	WP_096921852.1	RES family NAD+ phosphorylase	Toxin
CLM76_RS06715	1417806..1418255	-	450	WP_039178599.1	DUF2384 domain-containing protein	Antitoxin
CLM76_RS06720	1418467..1419831	+	1365	WP_039178596.1	diguanylate cyclase	-
CLM76_RS06725	1419850..1420401	+	552	WP_096921853.1	copper chaperone PCu(A)C	-
CLM76_RS06730	1420423..1421787	-	1365	WP_096921854.1	PepSY domain-containing protein	-
CLM76_RS06735	1421908..1422303	-	396	WP_096921855.1	DUF2946 domain-containing protein	-
CLM76_RS06740	1422496..1422834	-	339	WP_096921856.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (6-149)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (31-90)

Sequences

Toxin

Protein

• Length: 155 a.a.
• Molecular weight: 16913.23 Da
• Isoelectric Point: 4.5094

>T85820 WP_096921852.1 NZ_CP023656:c1417809-1417345 [Halomonas hydrothermalis]
MSEVTAYRLVKRKFQESAFDGEGARLYGGRWNSPGNACVYVASSESLALLEIMVHLESYRLLNAYALLRLTLPKQSILSV
GTEDLPENWREAPAPAETADLGDGWLASGQSLALALPSVVVPRELNYMLNPAHPLFEQAVASAEELPFQPDPRL

Nucleotide

• Length: 465 bp

>T85820 NZ_CP023656:c1417809-1417345 [Halomonas hydrothermalis]
ATGAGCGAGGTCACCGCTTACCGGCTGGTGAAGCGCAAGTTTCAGGAGAGCGCGTTTGATGGCGAGGGCGCACGGCTTTA
CGGCGGGCGCTGGAACAGCCCAGGCAATGCCTGTGTGTACGTAGCCAGCTCAGAGTCGTTGGCGCTGCTGGAAATCATGG
TGCATCTGGAAAGCTATCGGCTGCTCAATGCCTATGCGCTGCTGCGACTGACGCTGCCCAAACAGAGCATTTTGAGCGTT
GGAACGGAAGATTTACCCGAAAACTGGCGGGAAGCGCCAGCACCTGCGGAAACCGCCGACCTGGGCGATGGCTGGCTAGC
CTCCGGCCAGAGCCTGGCGCTGGCCCTGCCCAGCGTGGTGGTGCCGAGAGAGCTTAATTACATGCTCAACCCGGCCCACC
CCTTGTTCGAGCAAGCCGTTGCCAGCGCCGAGGAACTGCCGTTTCAACCCGATCCACGGCTGTAA

Antitoxin

Protein

• Length: 150 a.a.
• Molecular weight: 16553.99 Da
• Isoelectric Point: 10.2591

>AT85820 WP_039178599.1 NZ_CP023656:c1418255-1417806 [Halomonas hydrothermalis]
MAATFSQYQPTKAVASGYWQQIGLPARGRKLHELLHEGVEYRVYPRLAKVSGIEQKALARYVDIPSATLSRRAKSGRFKM
AESDRLYRFAELFKAALDLFEGDAEGARAWLLKPNAGLGGRRPVEMSATSAEYQTVLNLIGRLEHGVSV

Nucleotide

• Length: 450 bp

>AT85820 NZ_CP023656:c1418255-1417806 [Halomonas hydrothermalis]
ATGGCCGCTACCTTCTCCCAATATCAACCCACCAAAGCCGTGGCCTCCGGCTATTGGCAGCAAATTGGCCTGCCTGCGCG
AGGGCGTAAACTGCATGAGCTGCTGCATGAGGGGGTGGAGTACCGGGTCTACCCAAGGCTTGCCAAGGTGTCAGGTATCG
AGCAGAAGGCGCTGGCGCGCTATGTGGATATCCCGTCCGCCACACTGAGCCGCCGCGCCAAGTCAGGCCGCTTCAAGATG
GCGGAAAGCGACCGGCTGTATCGCTTTGCCGAGCTTTTCAAAGCGGCGCTGGATCTGTTCGAGGGTGACGCGGAAGGTGC
CCGCGCCTGGCTGCTCAAACCCAATGCCGGGCTAGGCGGACGTCGCCCCGTCGAAATGAGCGCCACCTCGGCGGAGTACC
AGACGGTGCTGAATCTGATCGGGCGGTTGGAGCACGGGGTGTCGGTATGA