Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2443149..2443383 | Replicon | chromosome |
| Accession | NZ_CP023645 | ||
| Organism | Shigella sonnei strain CFSAN030807 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2443150..2443253 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2443149..2443383 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AT852_RS13625 | 2439583..2439843 | + | 261 | WP_077447296.1 | excisionase | - |
| AT852_RS13630 | 2439872..2440326 | + | 455 | Protein_2462 | IS1-like element IS1A family transposase | - |
| AT852_RS13635 | 2440421..2441649 | + | 1229 | WP_088895425.1 | IS3-like element IS2 family transposase | - |
| AT852_RS13640 | 2441660..2441905 | + | 246 | Protein_2464 | IS1 family transposase | - |
| AT852_RS13645 | 2441942..2443018 | + | 1077 | WP_001189101.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2443149..2443383 | + | 235 | - | - | Antitoxin |
| - | 2443150..2443253 | - | 104 | - | - | Toxin |
| AT852_RS13650 | 2443411..2443752 | - | 342 | WP_000976476.1 | YebY family protein | - |
| AT852_RS13655 | 2443765..2444637 | - | 873 | WP_000879296.1 | copper homeostasis membrane protein CopD | - |
| AT852_RS13660 | 2444641..2445015 | - | 375 | WP_000168735.1 | CopC domain-containing protein YobA | - |
| AT852_RS13665 | 2445154..2445384 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| AT852_RS13670 | 2445486..2446142 | + | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein YobB | - |
| AT852_RS13675 | 2446166..2446828 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 | 2416188..2450793 | 34605 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T85806 NZ_CP023645:c2443253-2443150 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT85806 NZ_CP023645:2443149-2443383 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
