Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 2162954..2163488 Replicon chromosome
Accession NZ_CP023523
Organism Burkholderia gladioli pv. gladioli strain FDAARGOS_389

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag CO712_RS28200 Protein ID WP_096751909.1
Coordinates 2162954..2163253 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag CO712_RS28205 Protein ID WP_096751910.1
Coordinates 2163243..2163488 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CO712_RS28185 2158752..2159390 - 639 WP_096751907.1 DUF892 family protein -
CO712_RS28190 2159511..2160224 + 714 WP_124076621.1 hypothetical protein -
CO712_RS28195 2160495..2162663 + 2169 WP_096752918.1 glycogen debranching protein GlgX -
CO712_RS28200 2162954..2163253 - 300 WP_096751909.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CO712_RS28205 2163243..2163488 - 246 WP_096751910.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
CO712_RS28210 2163885..2164754 - 870 WP_096751911.1 type 1 glutamine amidotransferase domain-containing protein -
CO712_RS28215 2164785..2165594 - 810 WP_096751912.1 SDR family oxidoreductase -
CO712_RS28220 2165854..2166801 + 948 WP_096751913.1 GlxA family transcriptional regulator -
CO712_RS28225 2166929..2167324 - 396 WP_036032485.1 tautomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-94)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11761.19 Da        Isoelectric Point: 4.9047

>T81460 WP_096751909.1 NZ_CP023523:c2163253-2162954 [Burkholderia gladioli pv. gladioli]
MWAEARAVRLTPLAEADLEDIWTYTFEQWSLEQAERYVGDLIEAFERLARGDWVGRSSRASDDYRRYLVGSHVIFYQETK
ATLDVIRVLHQRMDVDRHL

Download         Length: 300 bp

>T81460 NZ_CP023523:c2163253-2162954 [Burkholderia gladioli pv. gladioli]
ATGTGGGCTGAGGCACGGGCGGTGCGATTGACGCCGTTGGCCGAGGCGGATCTCGAGGATATCTGGACCTACACGTTCGA
GCAGTGGTCACTCGAGCAGGCCGAGCGCTACGTGGGCGACCTGATTGAGGCGTTCGAGCGCCTGGCACGCGGCGATTGGG
TAGGGCGATCCAGCCGCGCGAGCGATGATTATCGGCGTTACCTGGTGGGATCTCACGTGATCTTCTATCAGGAAACGAAG
GCTACCCTAGACGTGATTCGCGTGCTGCATCAGCGCATGGACGTTGACCGGCATTTGTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8627.76 Da        Isoelectric Point: 8.7303

>AT81460 WP_096751910.1 NZ_CP023523:c2163488-2163243 [Burkholderia gladioli pv. gladioli]
MPRNTSISLGDHLTQFVDTQVASGRYGSASDVVRAGLRLLETQETELKALQEALRAGEASGAPAAFDGKAFLARMRVKHV
G

Download         Length: 246 bp

>AT81460 NZ_CP023523:c2163488-2163243 [Burkholderia gladioli pv. gladioli]
ATGCCGCGGAATACATCGATCTCGCTGGGGGATCACCTGACCCAGTTCGTGGATACCCAGGTCGCGTCCGGGCGCTATGG
CTCGGCCAGCGACGTGGTTCGGGCCGGTTTGCGGCTGCTCGAGACGCAGGAAACCGAGCTAAAGGCCTTGCAGGAAGCAC
TGCGCGCAGGTGAGGCATCCGGCGCGCCGGCGGCCTTCGACGGCAAGGCGTTCCTTGCGCGCATGCGCGTCAAGCATGTG
GGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References