Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2642109..2642380 Replicon chromosome
Accession NZ_CP023383
Organism Escherichia coli strain 1223

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2642147..2642250 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2642109..2642380 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CNQ49_RS13630 2639266..2640705 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CNQ49_RS13635 2640823..2641059 + 237 WP_001295499.1 DUF1480 family protein -
CNQ49_RS13640 2641164..2641355 + 192 WP_000457842.1 YebW family protein -
CNQ49_RS13645 2641356..2642012 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2642109..2642380 + 272 - - Antitoxin
- 2642147..2642250 - 104 - - Toxin
CNQ49_RS13650 2642408..2642749 - 342 WP_000976476.1 YebY family protein -
CNQ49_RS13655 2642762..2643634 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
CNQ49_RS13660 2643638..2644012 - 375 WP_000168747.1 CopC domain-containing protein YobA -
CNQ49_RS13665 2644151..2644381 + 231 WP_000916763.1 DNA polymerase III subunit theta -
CNQ49_RS13670 2644483..2645139 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
CNQ49_RS13675 2645163..2645825 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T81073 NZ_CP023383:c2642250-2642147 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT81073 NZ_CP023383:2642109-2642380 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References