Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2192065..2192336 Replicon chromosome
Accession NZ_CP023142
Organism Escherichia coli strain CFSAN061770

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2192195..2192298 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2192065..2192336 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CA696_RS11110 2188620..2189282 - 663 WP_000944256.1 exodeoxyribonuclease X -
CA696_RS11115 2189306..2189962 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
CA696_RS11120 2190064..2190294 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CA696_RS11125 2190433..2190807 + 375 WP_000204705.1 CopC domain-containing protein YobA -
CA696_RS11130 2190811..2191683 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
CA696_RS11135 2191696..2192037 + 342 WP_000976481.1 YebY family protein -
- 2192065..2192336 - 272 - - Antitoxin
- 2192195..2192298 + 104 - - Toxin
CA696_RS11140 2192433..2193089 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
CA696_RS11145 2193090..2193281 - 192 WP_001296140.1 YebW family protein -
CA696_RS11150 2193386..2193622 - 237 WP_001295499.1 DUF1480 family protein -
CA696_RS11155 2193740..2195179 - 1440 WP_001309555.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2184755..2208175 23420


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T80481 NZ_CP023142:2192195-2192298 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT80481 NZ_CP023142:c2192336-2192065 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References