80018

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2549566..2549750 Replicon chromosome
Accession NZ_CP022902
Organism Staphylococcus aureus strain 165

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag CGP98_RS13530 Protein ID WP_000482650.1
Coordinates 2549643..2549750 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2549566..2549626 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGP98_RS13505 2545096..2545263 - 168 WP_001790576.1 hypothetical protein -
CGP98_RS13515 2545494..2547227 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
CGP98_RS13520 2547252..2549015 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 2549566..2549626 + 61 - - Antitoxin
CGP98_RS13530 2549643..2549750 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
CGP98_RS13535 2549884..2550270 - 387 WP_000779358.1 flippase GtxA -
CGP98_RS13540 2550538..2551680 + 1143 WP_001176863.1 glycerate kinase -
CGP98_RS13545 2551740..2552399 + 660 WP_000831298.1 membrane protein -
CGP98_RS13550 2552581..2553792 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
CGP98_RS13555 2553915..2554388 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T80018 WP_000482650.1 NZ_CP022902:c2549750-2549643 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T80018 NZ_CP022902:c2549750-2549643 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT80018 NZ_CP022902:2549566-2549626 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References