Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 51978..52549 Replicon plasmid pEP1
Accession NZ_CP022726
Organism Erwinia persicina strain B64

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CI789_RS22960 Protein ID WP_062748521.1
Coordinates 52226..52549 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CI789_RS22955 Protein ID WP_062748581.1
Coordinates 51978..52226 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CI789_RS22920 47325..48292 - 968 Protein_51 hypothetical protein -
CI789_RS22925 48764..49111 + 348 Protein_52 tyrosine-type recombinase/integrase -
CI789_RS22930 49234..49620 + 387 WP_118666042.1 hypothetical protein -
CI789_RS22935 49893..50456 - 564 WP_118666044.1 pentapeptide repeat-containing protein -
CI789_RS22940 50456..50742 - 287 Protein_55 protein McbF -
CI789_RS22950 51065..51802 + 738 WP_118666162.1 site-specific integrase -
CI789_RS22955 51978..52226 + 249 WP_062748581.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CI789_RS22960 52226..52549 + 324 WP_062748521.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CI789_RS22965 53379..54122 - 744 WP_062748523.1 replication initiation protein RepE -
CI789_RS22970 54653..55852 + 1200 WP_062748525.1 AAA family ATPase -
CI789_RS22975 55861..56832 + 972 WP_118666048.1 ParB/RepB/Spo0J family partition protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..144252 144252


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-97)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12135.05 Da        Isoelectric Point: 10.5006

>T79653 WP_062748521.1 NZ_CP022726:52226-52549 [Erwinia persicina]
MSGKFTATLKFKALAKKEWDALNPSIREKFAKVLKKRAASYDALTMPANRLSLQHSCYKIKLRNDGYRLAYTVTSDDGGN
VRVTVTVVAVDRRDEIYEDLHKRLAGK

Download         Length: 324 bp

>T79653 NZ_CP022726:52226-52549 [Erwinia persicina]
ATGTCCGGAAAATTTACGGCCACCCTGAAGTTTAAGGCGCTGGCCAAAAAAGAATGGGACGCCCTGAACCCGTCCATCCG
GGAAAAGTTTGCGAAGGTGCTGAAGAAGCGCGCCGCGTCGTATGACGCGCTGACGATGCCGGCCAACCGGCTGTCCCTGC
AGCACAGCTGCTACAAGATAAAACTCAGAAATGACGGATACCGTCTGGCCTACACCGTCACCTCAGACGACGGGGGAAAC
GTGAGGGTCACGGTCACCGTGGTTGCCGTCGACCGGCGTGACGAGATCTACGAAGACCTGCATAAGCGGCTTGCCGGAAA
ATAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9184.44 Da        Isoelectric Point: 4.4328

>AT79653 WP_062748581.1 NZ_CP022726:51978-52226 [Erwinia persicina]
ITENILSRKTASITEFKKNPTAAMNESHGEPVAVLNHNKPAFYCVPPAMFELMFEHVSDALLLQKALDRAGDEEIDVVWD
DL

Download         Length: 249 bp

>AT79653 NZ_CP022726:51978-52226 [Erwinia persicina]
ATCACCGAAAACATTCTGAGCAGAAAAACCGCGTCCATCACCGAGTTCAAAAAGAACCCGACGGCCGCCATGAACGAGTC
GCACGGTGAGCCCGTTGCCGTGCTCAACCACAATAAACCCGCGTTTTACTGCGTCCCGCCGGCCATGTTTGAGCTGATGT
TCGAGCACGTCAGCGATGCACTGCTTCTGCAGAAAGCGCTCGACAGAGCAGGAGACGAGGAGATCGACGTCGTCTGGGAC
GACCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References