Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 374652..374886 Replicon chromosome
Accession NZ_CP022455
Organism Shigella sonnei strain 2015C-3794

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 374782..374885 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 374652..374886 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B9129_RS02225 371207..371869 - 663 WP_000944256.1 exodeoxyribonuclease X -
B9129_RS02230 371893..372549 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
B9129_RS02235 372651..372881 - 231 WP_000916763.1 DNA polymerase III subunit theta -
B9129_RS02240 373020..373394 + 375 WP_000168735.1 CopC domain-containing protein YobA -
B9129_RS02245 373398..374270 + 873 WP_000879296.1 copper homeostasis membrane protein CopD -
B9129_RS02250 374283..374624 + 342 WP_000976476.1 YebY family protein -
- 374652..374886 - 235 - - Antitoxin
- 374782..374885 + 104 - - Toxin
B9129_RS02255 375017..376093 - 1077 WP_001189101.1 phage integrase Arm DNA-binding domain-containing protein -
B9129_RS02260 376130..376375 - 246 Protein_398 IS1 family transposase -
B9129_RS02275 377756..378511 - 756 WP_001282649.1 IS21-like element ISSso4 family helper ATPase IstB -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - ipaH9.8 369150..404491 35341


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T79057 NZ_CP022455:374782-374885 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT79057 NZ_CP022455:c374886-374652 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References