Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 1323302..1323892 Replicon chromosome
Accession NZ_CP022427
Organism Pantoea ananatis strain YJ76

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag B7764_RS06215 Protein ID WP_029570198.1
Coordinates 1323560..1323892 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag B7764_RS06210 Protein ID WP_014605554.1
Coordinates 1323302..1323559 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7764_RS06175 1318582..1319007 + 426 WP_072136887.1 pentapeptide repeat-containing protein -
B7764_RS06180 1319299..1320537 - 1239 WP_089517234.1 MFS transporter -
B7764_RS06190 1321285..1322247 + 963 WP_041930826.1 ferrochelatase -
B7764_RS06200 1322748..1322954 + 207 WP_029570199.1 helix-turn-helix domain-containing protein -
B7764_RS06210 1323302..1323559 + 258 WP_014605554.1 antitoxin Antitoxin
B7764_RS06215 1323560..1323892 + 333 WP_029570198.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
B7764_RS06225 1324153..1324986 - 834 WP_089517237.1 DgsA anti-repressor MtfA -
B7764_RS06230 1325092..1325769 - 678 WP_013026204.1 hypothetical protein -
B7764_RS06235 1326381..1327085 + 705 WP_022623305.1 phosphohydrolase -
B7764_RS06240 1327159..1327413 + 255 WP_013026202.1 Arc family DNA-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-109)

Antitoxin

Antitoxin PemI-like

(4-83)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11930.65 Da        Isoelectric Point: 8.0219

>T79017 WP_029570198.1 NZ_CP022427:1323560-1323892 [Pantoea ananatis]
MDRGEIWLVSLDPNAGHEQSGRRPVLIVSPASFNQFTRLPVVVPVTNGGNFARAAGFTVSLNGAGTKTTGVIRCDQPRTL
DMEARNGKYLERIPEVIVNEVVARLEAILS

Download         Length: 333 bp

>T79017 NZ_CP022427:1323560-1323892 [Pantoea ananatis]
ATGGACAGAGGGGAAATCTGGCTCGTTTCACTAGATCCGAATGCCGGGCATGAACAAAGCGGAAGGCGTCCAGTACTGAT
TGTTTCTCCGGCGTCTTTTAATCAGTTTACGCGGCTACCTGTGGTTGTTCCCGTGACCAACGGCGGAAACTTTGCCCGCG
CAGCGGGGTTTACTGTTTCACTGAATGGCGCAGGAACGAAAACAACGGGGGTAATTCGTTGTGACCAGCCCAGAACCCTT
GATATGGAAGCCCGGAACGGCAAATATCTTGAACGGATACCTGAAGTTATTGTGAATGAAGTGGTGGCCAGACTGGAGGC
CATTCTGAGCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9253.73 Da        Isoelectric Point: 4.5821

>AT79017 WP_014605554.1 NZ_CP022427:1323302-1323559 [Pantoea ananatis]
MYTTRLKKVGGSVMLAVPPAVLKTLGLSTDSEVGMTIDSGCLIIEPQKRPRYSLEELLAQCDPHAEISEEGREWIDAPAV
GKELL

Download         Length: 258 bp

>AT79017 NZ_CP022427:1323302-1323559 [Pantoea ananatis]
ATGTATACCACTCGTCTGAAAAAGGTTGGCGGATCTGTCATGCTGGCGGTCCCTCCCGCCGTGCTGAAAACGCTGGGGCT
GTCGACGGACAGCGAAGTGGGCATGACCATTGATAGTGGCTGCCTCATAATTGAACCTCAAAAACGTCCCCGCTATTCAC
TCGAAGAACTACTGGCGCAGTGCGATCCGCACGCTGAAATTAGCGAAGAGGGTCGGGAATGGATTGATGCGCCTGCGGTG
GGCAAGGAGCTCCTGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References