Detailed information of TA system TA078920

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ygfYX/Cpta(toxin)
• Location: 1289760..1290429
• Replicon: chromosome
• Accession: NZ_CP022358
• Organism: Shewanella bicestrii strain JAB-1

Toxin (Protein)

• Gene name: ygfX
• Uniprot ID: -
• Locus tag: CF168_RS05680
• Protein ID: WP_167373572.1
• Coordinates: 1289989..1290429 (+)
• Length: 147 a.a.

Antitoxin (Protein)

• Gene name: ygfY
• Uniprot ID: -
• Locus tag: CF168_RS05675
• Protein ID: WP_084294861.1
• Coordinates: 1289760..1290008 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CF168_RS05650	1285397..1286203	+	807	WP_089067262.1	prolipoprotein diacylglyceryl transferase	-
CF168_RS05655	1286203..1286997	+	795	WP_089067263.1	thymidylate synthase	-
CF168_RS05660	1287115..1288284	+	1170	WP_089067264.1	Na+/H+ antiporter NhaA	-
CF168_RS05665	1288287..1288673	+	387	WP_086903301.1	hypothetical protein	-
CF168_RS05670	1288769..1289677	+	909	WP_086903346.1	transcriptional activator NhaR	-
CF168_RS05675	1289760..1290008	+	249	WP_084294861.1	succinate dehydrogenase assembly factor 2	Antitoxin
CF168_RS05680	1289989..1290429	+	441	WP_167373572.1	hypothetical protein	Toxin
CF168_RS05685	1290520..1292133	-	1614	WP_086903302.1	L-aspartate oxidase	-
CF168_RS05690	1292323..1292901	+	579	WP_011623604.1	RNA polymerase sigma factor RpoE	-
CF168_RS05695	1292928..1293551	+	624	WP_086903303.1	anti-sigma factor	-
CF168_RS05700	1293564..1294496	+	933	WP_011717876.1	MucB/RseB C-terminal domain-containing protein	-
CF168_RS05705	1294508..1294981	+	474	WP_089067265.1	SoxR reducing system RseC family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (5-134)

Antitoxin

• Flavinator of succinate dehydrogenase (7-77)

Sequences

Toxin

Protein

• Length: 147 a.a.
• Molecular weight: 17187.24 Da
• Isoelectric Point: 9.6140

>T78920 WP_167373572.1 NZ_CP022358:1289989-1290429 [Shewanella bicestrii]
VAERRHSFSVKASRDQRLSLVVFVCVCSTSLLIWPETDVVFWRVLKLIFAVLILGFLGYQLWRLRTWHCRFELNGKGEGW
LSTGEAFHVLPRTWVTPFVCLVYYQSADKLHLLPLWADMFSDREYRHLCRLLLKVKTQATSLRESL

Nucleotide

• Length: 441 bp

>T78920 NZ_CP022358:1289989-1290429 [Shewanella bicestrii]
GTGGCAGAGCGGCGCCATAGTTTTAGCGTAAAAGCCTCTCGCGACCAGCGACTCTCGTTGGTCGTTTTTGTTTGTGTCTG
CAGTACCTCTTTACTTATCTGGCCTGAAACGGACGTCGTATTTTGGCGTGTGCTTAAGTTGATATTCGCCGTTTTAATCC
TCGGATTCTTAGGCTATCAGTTATGGCGACTGAGGACTTGGCATTGTCGTTTTGAGCTGAATGGAAAAGGGGAAGGCTGG
CTCTCAACAGGGGAGGCGTTTCATGTTCTCCCCAGAACTTGGGTAACGCCCTTTGTTTGCTTGGTTTATTATCAGTCCGC
CGATAAGTTGCATCTCTTGCCCCTTTGGGCCGATATGTTTAGCGATAGGGAGTACCGCCACTTATGCCGACTGTTACTTA
AGGTTAAAACTCAGGCGACGAGCCTGCGCGAATCTCTTTAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9559.09 Da
• Isoelectric Point: 4.3313

>AT78920 WP_084294861.1 NZ_CP022358:1289760-1290008 [Shewanella bicestrii]
MELMNIARVRWACRRGMLELDVLFQPFVENVYQDLSDDDKALFIRLLECEDPELFAWFMGHEACPDAELARMVVQVRGRA
AP

Nucleotide

• Length: 249 bp

>AT78920 NZ_CP022358:1289760-1290008 [Shewanella bicestrii]
TTGGAGTTAATGAACATTGCACGGGTCCGCTGGGCATGTCGCCGCGGAATGCTCGAATTGGACGTCTTGTTCCAGCCTTT
CGTCGAAAATGTTTATCAGGATTTGTCGGATGACGACAAGGCCCTGTTTATTCGTTTACTCGAGTGTGAAGACCCTGAAT
TATTTGCCTGGTTTATGGGTCATGAAGCCTGTCCCGATGCAGAGCTTGCCCGCATGGTAGTGCAAGTCCGTGGCAGAGCG
GCGCCATAG