Detailed information of TA system TA078773

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pasABC/RelE-HTH
• Location: 1323319..1323802
• Replicon: chromosome
• Accession: NZ_CP022278
• Organism: Neisseria chenwenguii strain 10023

Toxin (Protein)

• Gene name: pasB
• Uniprot ID: -
• Locus tag: BG910_RS06580
• Protein ID: WP_089036153.1
• Coordinates: 1323527..1323802 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: pasA
• Uniprot ID: -
• Locus tag: BG910_RS06575
• Protein ID: WP_089037174.1
• Coordinates: 1323319..1323543 (+)
• Length: 75 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BG910_RS06535	1318696..1319157	+	462	WP_089035857.1	hypothetical protein	-
BG910_RS06540	1319132..1319692	+	561	WP_089035858.1	hypothetical protein	-
BG910_RS12275	1319697..1320035	+	339	WP_157694044.1	hypothetical protein	-
BG910_RS06545	1320063..1320305	+	243	WP_089036147.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
BG910_RS06550	1320295..1320582	+	288	WP_089036148.1	type II toxin-antitoxin system RelE/ParE family toxin	-
BG910_RS12280	1320615..1320743	-	129	WP_123805482.1	DUF4113 domain-containing protein	-
BG910_RS06555	1320721..1321587	-	867	WP_089036149.1	Fic family protein	-
BG910_RS06560	1321594..1321803	-	210	WP_089036150.1	hypothetical protein	-
BG910_RS06565	1321804..1322424	-	621	WP_089036151.1	recombinase family protein	-
BG910_RS06570	1322433..1323107	-	675	WP_089036152.1	Fic family protein	-
BG910_RS06575	1323319..1323543	+	225	WP_089037174.1	TraY domain-containing protein	Antitoxin
BG910_RS06580	1323527..1323802	+	276	WP_089036153.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BG910_RS06585	1323857..1324141	-	285	WP_089036154.1	virulence factor	-
BG910_RS06590	1324141..1324341	-	201	WP_089037175.1	DUF5397 family protein	-
BG910_RS06595	1324475..1325527	-	1053	WP_089036155.1	traS protein	-
BG910_RS06600	1325538..1326056	-	519	WP_089036156.1	plasmid mobilization relaxosome protein MobC	-
BG910_RS06605	1326118..1327320	-	1203	WP_089036157.1	hypothetical protein	-
BG910_RS06610	1327416..1327682	-	267	WP_089036158.1	hypothetical protein	-
BG910_RS06615	1327696..1328340	-	645	WP_089036159.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1328396..1329121	725

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-88)

Antitoxin

• Protein of unknown function DUF6290 (3-68)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10602.50 Da
• Isoelectric Point: 10.5519

>T78773 WP_089036153.1 NZ_CP022278:1323527-1323802 [Neisseria chenwenguii]
MAWKIELDKSAEKELKKLDKQTAIRILKFLHERISKSEDPRSIGEALKGSALGDYWKYRVGNCRIIAKIEDGIMKILVVR
IGNRREVYKSR

Nucleotide

• Length: 276 bp

>T78773 NZ_CP022278:1323527-1323802 [Neisseria chenwenguii]
ATGGCTTGGAAGATTGAGTTGGATAAATCGGCTGAAAAAGAGCTGAAAAAATTGGATAAGCAGACGGCCATACGGATTTT
GAAATTCTTACACGAAAGAATTTCAAAATCCGAAGACCCGAGAAGTATCGGCGAAGCCCTCAAAGGCTCAGCATTAGGGG
ATTATTGGAAATATCGGGTAGGTAATTGCCGAATCATCGCTAAAATCGAAGACGGAATCATGAAAATTCTGGTTGTACGA
ATCGGTAATCGACGCGAAGTGTACAAATCACGTTGA

Antitoxin

Protein

• Length: 75 a.a.
• Molecular weight: 8670.68 Da
• Isoelectric Point: 4.0948

>AT78773 WP_089037174.1 NZ_CP022278:1323319-1323543 [Neisseria chenwenguii]
MLAIRLPQEIENRLSVLAEKTGRTKTYYAREAILEYLDDLEDFYLAEQRYADIQAGKSETVSFEDVMRDYGLED

Nucleotide

• Length: 225 bp

>AT78773 NZ_CP022278:1323319-1323543 [Neisseria chenwenguii]
ATGCTTGCAATCCGTTTGCCTCAAGAAATCGAAAACCGCTTAAGTGTCTTGGCTGAGAAGACCGGTCGCACCAAAACCTA
TTATGCCCGAGAAGCGATTCTCGAATATTTAGATGACTTGGAAGATTTTTATCTAGCCGAACAACGCTATGCCGACATTC
AGGCCGGCAAAAGTGAAACTGTGTCGTTTGAAGATGTGATGAGGGACTATGGCTTGGAAGATTGA