Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 2333548..2334103 Replicon chromosome
Accession NZ_CP022121
Organism Dehalobacterium formicoaceticum strain DMC

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CEQ75_RS11340 Protein ID WP_089610717.1
Coordinates 2333825..2334103 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CEQ75_RS11335 Protein ID WP_089610715.1
Coordinates 2333548..2333838 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEQ75_RS11325 2329979..2330758 + 780 WP_089608935.1 IS21-like element helper ATPase IstB -
CEQ75_RS18400 2330945..2331391 - 447 WP_157677434.1 hypothetical protein -
CEQ75_RS11330 2331460..2332950 + 1491 WP_089610713.1 hypothetical protein -
CEQ75_RS11335 2333548..2333838 + 291 WP_089610715.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CEQ75_RS11340 2333825..2334103 + 279 WP_089610717.1 type II toxin-antitoxin system YafQ family toxin Toxin
CEQ75_RS18405 2334203..2334529 - 327 WP_157677435.1 hypothetical protein -
CEQ75_RS11345 2334638..2335744 + 1107 WP_157677436.1 hypothetical protein -
CEQ75_RS11350 2335674..2336147 + 474 WP_089612604.1 hypothetical protein -
CEQ75_RS11355 2336190..2337590 + 1401 WP_089610720.1 WG repeat-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10943.64 Da        Isoelectric Point: 9.8948

>T78497 WP_089610717.1 NZ_CP022121:2333825-2334103 [Dehalobacterium formicoaceticum]
MMKINRTSRFKKEYRQMMKRGYDSKPFEYVVGEIANGRALAEKYNDHALKGTFEGFRECHIQPDWLLIYFAEKDILTLTF
TRTGTHADLFKK

Download         Length: 279 bp

>T78497 NZ_CP022121:2333825-2334103 [Dehalobacterium formicoaceticum]
ATGATGAAGATTAACAGAACTTCCCGTTTCAAGAAAGAATACAGACAGATGATGAAGCGGGGCTATGATTCCAAACCGTT
TGAGTATGTGGTCGGAGAGATAGCAAATGGCCGGGCATTGGCAGAAAAATATAATGACCACGCCTTGAAAGGCACCTTTG
AAGGGTTCAGGGAGTGCCATATACAACCGGATTGGCTGCTGATATACTTTGCTGAAAAAGACATTTTGACGCTGACTTTC
ACACGGACTGGTACTCATGCTGATTTGTTTAAGAAATAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10326.73 Da        Isoelectric Point: 4.3431

>AT78497 WP_089610715.1 NZ_CP022121:2333548-2333838 [Dehalobacterium formicoaceticum]
MAKSETLHIRIEPAVKAGVEATLKTLGLSTTEAINIFLHQVILTGGLPFEVKNPQYNAETIAAMQEARDIAAGKVPAKSF
STIAELMDDLNSDDED

Download         Length: 291 bp

>AT78497 NZ_CP022121:2333548-2333838 [Dehalobacterium formicoaceticum]
ATGGCTAAATCGGAAACTCTGCATATTCGGATTGAACCAGCTGTTAAAGCCGGTGTTGAGGCCACGCTTAAAACATTGGG
ACTTTCAACCACTGAAGCGATTAATATATTTCTTCACCAGGTTATTCTCACTGGAGGGTTGCCTTTTGAGGTCAAAAACC
CTCAATATAATGCTGAAACCATTGCCGCCATGCAGGAAGCCCGTGATATTGCCGCTGGAAAAGTCCCGGCAAAAAGCTTT
AGTACAATAGCAGAGCTGATGGATGACTTGAACAGCGATGATGAAGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References