Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4131993..4132138 Replicon chromosome
Accession NZ_CP021939
Organism Klebsiella pneumoniae strain AR_0145

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4132000..4132102 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4131993..4132138 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM392_RS20755 4127524..4128957 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AM392_RS20760 4129073..4129312 + 240 WP_002911393.1 YebV family protein -
AM392_RS20765 4129410..4129601 + 192 WP_002911395.1 YebW family protein -
AM392_RS20770 4129598..4130251 - 654 WP_024622748.1 protein-serine/threonine phosphatase -
AM392_RS20775 4130408..4131376 + 969 WP_014907334.1 VirK/YbjX family protein -
AM392_RS28460 4131481..4131624 + 144 WP_038431282.1 Ecr family regulatory small membrane protein -
- 4131993..4132138 + 146 - - Antitoxin
- 4132000..4132102 - 103 - - Toxin
AM392_RS20785 4132261..4132599 - 339 WP_002911404.1 YebY family protein -
AM392_RS20790 4132616..4133485 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
AM392_RS20795 4133489..4133863 - 375 WP_039819395.1 CopC domain-containing protein YobA -
AM392_RS20800 4133976..4134206 + 231 WP_002911406.1 DNA polymerase III subunit theta -
AM392_RS20805 4134285..4134944 + 660 WP_002911407.1 exodeoxyribonuclease X -
AM392_RS20810 4134948..4137008 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T77935 NZ_CP021939:c4132102-4132000 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT77935 NZ_CP021939:4131993-4132138 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References