Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 114667..114811 | Replicon | chromosome |
| Accession | NZ_CP021685 | ||
| Organism | Klebsiella pneumoniae strain AR_0146 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 114673..114775 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 114667..114811 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AM393_RS00550 | 110440..110721 | + | 282 | WP_032419786.1 | hypothetical protein | - |
| AM393_RS00555 | 110731..111159 | + | 429 | WP_032419788.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| AM393_RS00560 | 111409..112914 | - | 1506 | WP_020956680.1 | hypothetical protein | - |
| AM393_RS00570 | 113703..114182 | - | 480 | WP_032419797.1 | lysis protein | - |
| AM393_RS00575 | 114181..114540 | + | 360 | WP_077253379.1 | tyrosine-type recombinase/integrase | - |
| - | 114667..114811 | + | 145 | - | - | Antitoxin |
| - | 114673..114775 | - | 103 | - | - | Toxin |
| AM393_RS00580 | 114934..115272 | - | 339 | WP_002911404.1 | YebY family protein | - |
| AM393_RS00585 | 115289..116158 | - | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| AM393_RS00590 | 116162..116536 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| AM393_RS00595 | 116649..116879 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| AM393_RS00600 | 116958..117617 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| AM393_RS00605 | 117621..119681 | - | 2061 | WP_004151449.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T76960 NZ_CP021685:c114775-114673 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT76960 NZ_CP021685:114667-114811 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
