Detailed information of TA system TA076621

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-Phd
• Location: 3798964..3799607
• Replicon: chromosome
• Accession: NZ_CP021431
• Organism: Yoonia vestfoldensis strain SMR4r

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: LOKVESSMR4R_RS19065
• Protein ID: WP_087212157.1
• Coordinates: 3799206..3799607 (+)
• Length: 134 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: LOKVESSMR4R_RS19060
• Protein ID: WP_087212154.1
• Coordinates: 3798964..3799206 (+)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LOKVESSMR4R_RS19035	3794161..3794430	-	270	WP_087212140.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
LOKVESSMR4R_RS19040	3794493..3794915	-	423	WP_087212143.1	hypothetical protein	-
LOKVESSMR4R_RS19045	3795235..3795915	-	681	WP_087212146.1	hypothetical protein	-
LOKVESSMR4R_RS19050	3796439..3797734	+	1296	WP_087212148.1	AAA family ATPase	-
LOKVESSMR4R_RS19055	3797738..3798859	+	1122	WP_087212151.1	ParB N-terminal domain-containing protein	-
LOKVESSMR4R_RS19060	3798964..3799206	+	243	WP_087212154.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
LOKVESSMR4R_RS19065	3799206..3799607	+	402	WP_087212157.1	type II toxin-antitoxin system VapC family toxin	Toxin
LOKVESSMR4R_RS19070	3799643..3800566	-	924	Protein_3783	tyrosine-type recombinase/integrase	-
LOKVESSMR4R_RS20345	3800599..3800769	+	171	WP_162290746.1	hypothetical protein	-
LOKVESSMR4R_RS19075	3800804..3801223	+	420	WP_024899711.1	phosphonate C-P lyase system protein PhnG	-
LOKVESSMR4R_RS19080	3801220..3801795	+	576	WP_157898282.1	phosphonate C-P lyase system protein PhnH	-
LOKVESSMR4R_RS19085	3801779..3802792	+	1014	WP_087212160.1	carbon-phosphorus lyase complex subunit PhnI	-
LOKVESSMR4R_RS19090	3802785..3803630	+	846	WP_036541494.1	alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase PhnJ	-
LOKVESSMR4R_RS19095	3803623..3804390	+	768	WP_036541488.1	ATP-binding cassette domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3794493..3836885	42392

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-117)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (2-48)

Sequences

Toxin

Protein

• Length: 134 a.a.
• Molecular weight: 14608.60 Da
• Isoelectric Point: 4.8891

>T76621 WP_087212157.1 NZ_CP021431:3799206-3799607 [Yoonia vestfoldensis]
MYILDTNVISAVRRPDRAPKVAAWLRGKAEQDLFLSVVTLGEIERGIRQQEARDPGFAQDLRSWLDQTIMLFSDRLLSFQ
AEDARIWGRLSAEIGHTGADLMIAASALRHGAIVVTGNVSDFAPTGAAVEDPF

Nucleotide

• Length: 402 bp

>T76621 NZ_CP021431:3799206-3799607 [Yoonia vestfoldensis]
ATGTACATACTCGACACGAACGTCATCTCGGCCGTGCGTCGTCCGGACCGCGCACCCAAGGTAGCCGCCTGGTTGCGAGG
CAAGGCAGAACAGGACCTCTTCCTGAGTGTTGTGACATTGGGCGAAATTGAGCGTGGCATTCGCCAGCAGGAAGCCCGGG
ACCCCGGGTTTGCGCAGGATCTTCGGTCTTGGCTTGATCAGACTATCATGCTGTTCTCGGATCGGTTGCTTTCTTTCCAG
GCCGAGGATGCCCGCATCTGGGGCCGGCTTTCGGCCGAGATAGGTCACACTGGCGCGGATCTAATGATTGCTGCGTCGGC
GCTACGCCACGGCGCGATTGTTGTTACGGGGAATGTGAGTGACTTTGCGCCAACAGGGGCTGCGGTCGAAGATCCGTTCT
GA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8603.78 Da
• Isoelectric Point: 8.7041

>AT76621 WP_087212154.1 NZ_CP021431:3798964-3799206 [Yoonia vestfoldensis]
MWTVQDAKNKFSAVVDAALAGTPQEVTRRGKPAVVVLSADEYHRLVEGAVKARGSFAEHLMAFPGGDFPRASATLRDVSF

Nucleotide

• Length: 243 bp

>AT76621 NZ_CP021431:3798964-3799206 [Yoonia vestfoldensis]
ATGTGGACCGTTCAGGATGCGAAGAACAAGTTCAGTGCGGTGGTTGATGCCGCGTTGGCAGGGACCCCGCAAGAGGTGAC
GCGCCGTGGCAAGCCTGCGGTTGTTGTGCTGTCTGCCGATGAATATCATAGACTTGTTGAAGGGGCTGTGAAGGCGCGGG
GAAGCTTTGCAGAGCATTTGATGGCATTTCCCGGGGGCGATTTCCCACGGGCATCTGCCACCCTGCGTGATGTAAGCTTT
TGA