Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hipBA/HipA-HipB |
Location | 2830582..2832146 | Replicon | chromosome |
Accession | NZ_CP021377 | ||
Organism | Oceanisphaera profunda strain SM1222 |
Toxin (Protein)
Gene name | hipA | Uniprot ID | - |
Locus tag | CBP31_RS12525 | Protein ID | WP_087037789.1 |
Coordinates | 2830582..2831895 (-) | Length | 438 a.a. |
Antitoxin (Protein)
Gene name | hipB | Uniprot ID | - |
Locus tag | CBP31_RS12530 | Protein ID | WP_087037791.1 |
Coordinates | 2831895..2832146 (-) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CBP31_RS12510 | 2826118..2829036 | - | 2919 | WP_087037783.1 | DEAD/DEAH box helicase family protein | - |
CBP31_RS12515 | 2829033..2829635 | - | 603 | WP_087037785.1 | class I SAM-dependent methyltransferase | - |
CBP31_RS12520 | 2829792..2830277 | + | 486 | WP_087037787.1 | nucleoside deaminase | - |
CBP31_RS12525 | 2830582..2831895 | - | 1314 | WP_087037789.1 | type II toxin-antitoxin system HipA family toxin | Toxin |
CBP31_RS12530 | 2831895..2832146 | - | 252 | WP_087037791.1 | helix-turn-helix domain-containing protein | Antitoxin |
CBP31_RS12535 | 2832826..2833947 | - | 1122 | WP_087038750.1 | flagellar assembly protein T N-terminal domain-containing protein | - |
CBP31_RS12540 | 2834311..2835060 | + | 750 | WP_087037793.1 | hypothetical protein | - |
CBP31_RS12545 | 2835074..2835454 | + | 381 | WP_087038753.1 | LPP20 family lipoprotein | - |
CBP31_RS12555 | 2836305..2836718 | - | 414 | WP_087037797.1 | flagellar protein FlgN | - |
CBP31_RS12560 | 2836720..2837040 | - | 321 | WP_087037799.1 | flagellar biosynthesis anti-sigma factor FlgM | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 438 a.a. Molecular weight: 48554.47 Da Isoelectric Point: 7.8881
>T76555 WP_087037789.1 NZ_CP021377:c2831895-2830582 [Oceanisphaera profunda]
MAQLTIAMNGYQVGTLYRSSSGTHEFWYHQDWLDMPGSRPISLSLPLGKQRFKGEEVYNFFDNLLPDKMQTRQRIVARHQ
AASSQPFDLLAKIGMDSVGALQIYPASQQPEGVRSIHCKKLTQSALLNILQGYQSNAPLGMISGEEDFRISIAGAQEKTA
LLKQNENWYLPLGSTPTTHIIKLPIGTIQSHSHTIDLSTSVENELVCLRLAGALGLEVAAADILDVRGFRALSVARFDRR
RSSDGQWIMRLPQEDFCQVLGVSPGLKYESDGGPNIVKIMSYLLGSAQPEQDRATFMLAQVVFWLLAATDGHAKNFSVFL
LPNGAFRLTPLYDILSAYPVMGGSGLSERKIKMAMALQGSSGRHYQWYNLFPRHFLTTARAAGFDETAMQTILDDVRDRV
PTAINSVRQSLPENFPADISEVIFSGVEKRAKRLDQN
MAQLTIAMNGYQVGTLYRSSSGTHEFWYHQDWLDMPGSRPISLSLPLGKQRFKGEEVYNFFDNLLPDKMQTRQRIVARHQ
AASSQPFDLLAKIGMDSVGALQIYPASQQPEGVRSIHCKKLTQSALLNILQGYQSNAPLGMISGEEDFRISIAGAQEKTA
LLKQNENWYLPLGSTPTTHIIKLPIGTIQSHSHTIDLSTSVENELVCLRLAGALGLEVAAADILDVRGFRALSVARFDRR
RSSDGQWIMRLPQEDFCQVLGVSPGLKYESDGGPNIVKIMSYLLGSAQPEQDRATFMLAQVVFWLLAATDGHAKNFSVFL
LPNGAFRLTPLYDILSAYPVMGGSGLSERKIKMAMALQGSSGRHYQWYNLFPRHFLTTARAAGFDETAMQTILDDVRDRV
PTAINSVRQSLPENFPADISEVIFSGVEKRAKRLDQN
Download Length: 1314 bp
>T76555 NZ_CP021377:c2831895-2830582 [Oceanisphaera profunda]
ATGGCACAGCTAACTATCGCCATGAATGGCTACCAAGTAGGCACGCTATATCGATCATCATCTGGTACTCATGAGTTTTG
GTACCATCAAGACTGGCTCGATATGCCCGGCTCTCGCCCCATTTCTCTATCCCTACCATTAGGCAAACAACGCTTCAAAG
GTGAAGAGGTATACAATTTTTTTGATAACCTATTACCCGACAAAATGCAGACTCGACAGCGCATTGTCGCTCGTCATCAG
GCAGCTTCAAGTCAGCCCTTTGATCTATTAGCCAAAATTGGGATGGATAGCGTGGGGGCTCTACAGATCTACCCTGCCAG
TCAGCAACCAGAAGGGGTTAGAAGCATTCATTGTAAGAAGTTAACTCAATCGGCGCTGCTGAATATCTTGCAAGGTTATC
AAAGCAATGCACCATTGGGGATGATTAGCGGTGAAGAAGACTTTCGAATTTCGATTGCCGGCGCACAAGAAAAAACTGCG
CTACTCAAACAAAACGAAAATTGGTATCTACCGCTAGGCAGTACACCCACCACACACATTATCAAGTTACCGATAGGTAC
CATCCAAAGTCATTCTCATACCATTGATTTAAGTACTAGCGTCGAAAATGAATTGGTTTGCTTACGCTTAGCCGGTGCAC
TTGGTTTGGAAGTAGCAGCCGCGGATATTCTTGACGTGCGAGGCTTTCGAGCATTGTCCGTGGCCCGCTTTGACCGGCGA
CGATCATCTGACGGTCAATGGATTATGCGCTTACCACAAGAAGACTTTTGTCAGGTTCTAGGCGTATCACCCGGCCTTAA
ATACGAAAGTGATGGAGGCCCAAATATTGTCAAGATTATGAGTTACCTATTGGGCTCAGCTCAACCAGAACAAGATAGAG
CAACCTTCATGCTAGCCCAAGTCGTATTCTGGCTATTAGCAGCAACGGATGGACACGCCAAAAACTTTTCAGTTTTTTTA
CTACCAAATGGGGCCTTCAGACTCACACCACTCTATGACATTCTTTCGGCCTACCCAGTTATGGGTGGCTCGGGGCTCTC
GGAGCGAAAAATCAAAATGGCCATGGCCCTACAAGGATCATCTGGCCGCCATTATCAATGGTATAACCTTTTTCCTCGCC
ACTTTCTAACCACTGCCCGTGCGGCCGGATTTGATGAAACAGCCATGCAAACGATTTTAGATGACGTTAGAGACCGAGTT
CCAACGGCTATCAATAGCGTCAGACAGTCGTTACCTGAAAATTTTCCTGCTGATATAAGTGAAGTCATTTTCTCCGGTGT
AGAAAAACGAGCAAAGCGGCTAGACCAAAACTAA
ATGGCACAGCTAACTATCGCCATGAATGGCTACCAAGTAGGCACGCTATATCGATCATCATCTGGTACTCATGAGTTTTG
GTACCATCAAGACTGGCTCGATATGCCCGGCTCTCGCCCCATTTCTCTATCCCTACCATTAGGCAAACAACGCTTCAAAG
GTGAAGAGGTATACAATTTTTTTGATAACCTATTACCCGACAAAATGCAGACTCGACAGCGCATTGTCGCTCGTCATCAG
GCAGCTTCAAGTCAGCCCTTTGATCTATTAGCCAAAATTGGGATGGATAGCGTGGGGGCTCTACAGATCTACCCTGCCAG
TCAGCAACCAGAAGGGGTTAGAAGCATTCATTGTAAGAAGTTAACTCAATCGGCGCTGCTGAATATCTTGCAAGGTTATC
AAAGCAATGCACCATTGGGGATGATTAGCGGTGAAGAAGACTTTCGAATTTCGATTGCCGGCGCACAAGAAAAAACTGCG
CTACTCAAACAAAACGAAAATTGGTATCTACCGCTAGGCAGTACACCCACCACACACATTATCAAGTTACCGATAGGTAC
CATCCAAAGTCATTCTCATACCATTGATTTAAGTACTAGCGTCGAAAATGAATTGGTTTGCTTACGCTTAGCCGGTGCAC
TTGGTTTGGAAGTAGCAGCCGCGGATATTCTTGACGTGCGAGGCTTTCGAGCATTGTCCGTGGCCCGCTTTGACCGGCGA
CGATCATCTGACGGTCAATGGATTATGCGCTTACCACAAGAAGACTTTTGTCAGGTTCTAGGCGTATCACCCGGCCTTAA
ATACGAAAGTGATGGAGGCCCAAATATTGTCAAGATTATGAGTTACCTATTGGGCTCAGCTCAACCAGAACAAGATAGAG
CAACCTTCATGCTAGCCCAAGTCGTATTCTGGCTATTAGCAGCAACGGATGGACACGCCAAAAACTTTTCAGTTTTTTTA
CTACCAAATGGGGCCTTCAGACTCACACCACTCTATGACATTCTTTCGGCCTACCCAGTTATGGGTGGCTCGGGGCTCTC
GGAGCGAAAAATCAAAATGGCCATGGCCCTACAAGGATCATCTGGCCGCCATTATCAATGGTATAACCTTTTTCCTCGCC
ACTTTCTAACCACTGCCCGTGCGGCCGGATTTGATGAAACAGCCATGCAAACGATTTTAGATGACGTTAGAGACCGAGTT
CCAACGGCTATCAATAGCGTCAGACAGTCGTTACCTGAAAATTTTCCTGCTGATATAAGTGAAGTCATTTTCTCCGGTGT
AGAAAAACGAGCAAAGCGGCTAGACCAAAACTAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9474.63 Da Isoelectric Point: 7.2040
>AT76555 WP_087037791.1 NZ_CP021377:c2832146-2831895 [Oceanisphaera profunda]
MKVTSAHQLSHVLQDQRKQQGQSQTLVARKVGLRQDTVSKFENTPDGTRLDTLFKLLSALDLELEVKPRGSAPNTTEQWQ
EEW
MKVTSAHQLSHVLQDQRKQQGQSQTLVARKVGLRQDTVSKFENTPDGTRLDTLFKLLSALDLELEVKPRGSAPNTTEQWQ
EEW
Download Length: 252 bp
>AT76555 NZ_CP021377:c2832146-2831895 [Oceanisphaera profunda]
ATGAAAGTAACTTCTGCCCATCAACTCAGCCATGTATTACAAGATCAGCGTAAACAACAAGGTCAATCACAGACCCTAGT
GGCTCGCAAGGTTGGGCTGCGCCAAGATACCGTTTCAAAATTCGAAAACACGCCCGACGGTACTCGCCTCGATACCCTGT
TCAAATTGCTTTCGGCATTGGATTTAGAGCTAGAAGTTAAGCCGCGTGGCAGTGCTCCTAATACTACTGAGCAATGGCAG
GAGGAATGGTAA
ATGAAAGTAACTTCTGCCCATCAACTCAGCCATGTATTACAAGATCAGCGTAAACAACAAGGTCAATCACAGACCCTAGT
GGCTCGCAAGGTTGGGCTGCGCCAAGATACCGTTTCAAAATTCGAAAACACGCCCGACGGTACTCGCCTCGATACCCTGT
TCAAATTGCTTTCGGCATTGGATTTAGAGCTAGAAGTTAAGCCGCGTGGCAGTGCTCCTAATACTACTGAGCAATGGCAG
GAGGAATGGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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