Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1671532..1672322 Replicon chromosome
Accession NZ_CP021362
Organism Acidovorax carolinensis strain P3

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag CBP35_RS07720 Protein ID WP_086927476.1
Coordinates 1671822..1672322 (+) Length 167 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag CBP35_RS07715 Protein ID WP_086927477.1
Coordinates 1671532..1671825 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CBP35_RS07710 1669509..1670846 + 1338 WP_086910894.1 IS1182 family transposase -
CBP35_RS07715 1671532..1671825 + 294 WP_086927477.1 DUF1778 domain-containing protein Antitoxin
CBP35_RS07720 1671822..1672322 + 501 WP_086927476.1 GNAT family N-acetyltransferase Toxin
CBP35_RS21470 1672319..1672480 + 162 WP_157896735.1 hypothetical protein -
CBP35_RS07730 1672909..1674756 + 1848 WP_086927475.1 hypothetical protein -
CBP35_RS21890 1674795..1675280 + 486 WP_204247867.1 methyltransferase domain-containing protein -
CBP35_RS21895 1675277..1675633 + 357 WP_204247868.1 hypothetical protein -
CBP35_RS07740 1675630..1676568 + 939 WP_086927473.1 glycosyltransferase family 2 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-144)

Antitoxin

Vibrio phage ICP1, Orf50

(1-96)


Sequences

Toxin        


Download         Length: 167 a.a.        Molecular weight: 18300.18 Da        Isoelectric Point: 9.5707

>T76544 WP_086927476.1 NZ_CP021362:1671822-1672322 [Acidovorax carolinensis]
VTLRAPEPLAAQHRLEGFDCGKPALNDWLLRHARQAQGSGSAKTFVVAEDDGHVAGYFSLTVGKVDTLEAPERIRKGMGQ
YPLPVVILARLAVSIHDQGRGIGFGLLQDAIRRTMLIAEQAGIRAMLTHPIDDDAAQFYTRFGFIASPLREQQLLLLLKD
AKKFIR

Download         Length: 501 bp

>T76544 NZ_CP021362:1671822-1672322 [Acidovorax carolinensis]
GTGACGTTGCGCGCACCGGAGCCACTGGCTGCCCAGCATCGGCTGGAAGGTTTTGATTGCGGTAAACCCGCGCTCAACGA
CTGGCTGTTACGCCACGCCCGCCAGGCGCAGGGCAGTGGATCGGCCAAGACCTTCGTTGTTGCCGAGGACGATGGCCACG
TAGCGGGCTACTTCAGCCTGACCGTGGGTAAAGTCGACACGCTGGAGGCACCGGAGCGCATCCGCAAGGGGATGGGGCAG
TACCCTTTGCCAGTGGTGATTCTGGCGAGGCTGGCAGTATCAATTCACGATCAGGGGCGAGGAATCGGCTTTGGCCTGCT
GCAGGATGCGATTCGTCGCACGATGCTGATTGCCGAGCAGGCTGGCATCCGGGCGATGTTGACCCATCCCATCGATGATG
ACGCAGCGCAGTTCTACACCCGTTTCGGGTTCATCGCGTCACCGCTGCGTGAGCAGCAACTTCTGCTGTTGCTGAAGGAT
GCGAAGAAGTTCATCCGATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10703.19 Da        Isoelectric Point: 5.8188

>AT76544 WP_086927477.1 NZ_CP021362:1671532-1671825 [Acidovorax carolinensis]
MTAVASSPSARSARLGLRATPEQEVVLRRAAEVAHKSLTDFILDSACLAAEQTLLDQRLFMVSGSQYQALMDLLDRPEQA
NDGLRDLFARKAPWDTK

Download         Length: 294 bp

>AT76544 NZ_CP021362:1671532-1671825 [Acidovorax carolinensis]
ATGACTGCTGTTGCATCGTCGCCTTCCGCACGGTCCGCCCGCCTCGGGCTGCGCGCCACCCCCGAACAGGAGGTGGTGTT
GCGTCGGGCTGCTGAGGTTGCCCACAAGTCGCTGACCGACTTCATTCTCGACAGCGCCTGCCTGGCTGCCGAGCAAACCC
TACTGGATCAGCGCCTGTTTATGGTGTCGGGCAGTCAGTACCAGGCTCTGATGGATCTGCTCGATCGCCCCGAACAGGCC
AACGACGGTTTGCGTGATCTGTTTGCCCGAAAGGCGCCCTGGGACACGAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References