Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1878664..1878932 Replicon chromosome
Accession NZ_CP021288
Organism Escherichia coli strain PA45B

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1878702..1878804 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1878664..1878932 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PA45B_RS09910 1875821..1877260 + 1440 WP_001351128.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
PA45B_RS09915 1877378..1877614 + 237 WP_001295499.1 DUF1480 family protein -
PA45B_RS09920 1877719..1877910 + 192 WP_001296140.1 YebW family protein -
PA45B_RS09925 1877911..1878567 - 657 WP_000812741.1 protein-serine/threonine phosphatase -
- 1878664..1878932 + 269 - - Antitoxin
- 1878702..1878804 - 103 - - Toxin
PA45B_RS09930 1878962..1879303 - 342 WP_000984819.1 YebY family protein -
PA45B_RS09935 1879316..1880188 - 873 WP_000879320.1 copper homeostasis membrane protein CopD -
PA45B_RS09940 1880192..1880566 - 375 WP_000168747.1 CopC domain-containing protein YobA -
PA45B_RS09945 1880705..1880935 + 231 WP_000916763.1 DNA polymerase III subunit theta -
PA45B_RS09950 1881037..1881693 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
PA45B_RS09955 1881716..1882378 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T76412 NZ_CP021288:c1878804-1878702 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT76412 NZ_CP021288:1878664-1878932 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References