75982

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2428769..2428953 Replicon chromosome
Accession NZ_CP021105
Organism Staphylococcus aureus strain CC5

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag B4893_RS12660 Protein ID WP_000482652.1
Coordinates 2428846..2428953 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2428769..2428829 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B4893_RS12635 2424224..2424391 - 168 Protein_2324 hypothetical protein -
B4893_RS12645 2424622..2426355 - 1734 WP_107383448.1 ABC transporter ATP-binding protein/permease -
B4893_RS12650 2426380..2428143 - 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
- 2428769..2428829 + 61 - - Antitoxin
B4893_RS12660 2428846..2428953 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
B4893_RS12665 2429087..2429473 - 387 WP_000779360.1 flippase GtxA -
B4893_RS12670 2429741..2430883 + 1143 WP_001176863.1 glycerate kinase -
B4893_RS12675 2430943..2431602 + 660 WP_000831298.1 membrane protein -
B4893_RS12680 2431784..2432995 + 1212 WP_094659772.1 multidrug effflux MFS transporter -
B4893_RS12685 2433118..2433591 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T75982 WP_000482652.1 NZ_CP021105:c2428953-2428846 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T75982 NZ_CP021105:c2428953-2428846 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT75982 NZ_CP021105:2428769-2428829 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References