Detailed information of TA system TA075927

Bioinformatically predicted

Overview

TA module

• Type: VII
• Classification (family/domain): HepT-MntA/HepT(toxin)
• Location: 3945799..3946700
• Replicon: chromosome
• Accession: NZ_CP021056
• Organism: Richelia sinica FACHB-800 strain FACHB 800

Toxin (Protein)

• Gene name: hepT
• Uniprot ID: -
• Locus tag: B6N60_RS16600
• Protein ID: WP_190602326.1
• Coordinates: 3946248..3946700 (+)
• Length: 151 a.a.

Antitoxin (Protein)

• Gene name: mntA
• Uniprot ID: -
• Locus tag: B6N60_RS16595
• Protein ID: WP_190602323.1
• Coordinates: 3945799..3946251 (+)
• Length: 151 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B6N60_RS16570 (B6N60_03664)	3940942..3941331	+	390	WP_190602314.1	DUF5615 family PIN-like protein	-
B6N60_RS16575 (B6N60_03665)	3941382..3942248	-	867	WP_190602316.1	transcriptional regulator	-
B6N60_RS16580 (B6N60_03666)	3942451..3944628	+	2178	WP_190602317.1	type I-D CRISPR-associated helicase Cas3'	-
B6N60_RS16585 (B6N60_03667)	3944891..3945205	+	315	WP_190602319.1	hypothetical protein	-
B6N60_RS16590	3945434..3945670	+	237	WP_190602321.1	hypothetical protein	-
B6N60_RS16595 (B6N60_03670)	3945799..3946251	+	453	WP_190602323.1	nucleotidyltransferase domain-containing protein	Antitoxin
B6N60_RS16600 (B6N60_03671)	3946248..3946700	+	453	WP_190602326.1	DUF86 domain-containing protein	Toxin
B6N60_RS16605 (B6N60_03672)	3946684..3950034	+	3351	WP_190602327.1	type I-D CRISPR-associated protein Cas10d/Csc3	-
B6N60_RS16610 (B6N60_03673)	3950110..3951120	+	1011	WP_190602329.1	type I-D CRISPR-associated protein Cas7/Csc2	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease HepT-like (16-134)

Antitoxin

• Polymerase beta, nucleotidyltransferase (21-111)

Sequences

Toxin

Protein

• Length: 151 a.a.
• Molecular weight: 17461.88 Da
• Isoelectric Point: 4.6268

>T75927 WP_190602326.1 NZ_CP021056:3946248-3946700 [Richelia sinica FACHB-800]
MSNIDSEIIVARLRLINKYYNTLEEFRSISLDEFLSDFRQQLVVERLLQLMTQAAIDINDHILSKLNPGQAFTNFEAFIE
LGQYQIITPELAKQIAPSSGLRNRLVHEYDDIDPNQVFKAISFALQQYPLYVRQINSYLISLEEDNGYKK

Nucleotide

• Length: 453 bp

>T75927 NZ_CP021056:3946248-3946700 [Richelia sinica FACHB-800]
ATGAGTAATATAGACTCGGAAATAATTGTAGCTAGGCTCAGGCTAATTAATAAATATTACAACACATTAGAAGAATTCCG
CTCCATTAGCCTTGATGAATTTTTGTCTGATTTTCGTCAACAACTTGTTGTAGAAAGACTTCTGCAATTAATGACTCAAG
CCGCAATAGACATCAACGACCATATATTGTCAAAGCTAAACCCTGGGCAAGCTTTCACTAATTTTGAGGCTTTTATCGAA
TTGGGTCAATATCAAATCATTACACCAGAACTAGCTAAACAAATTGCACCATCGTCAGGATTAAGAAATCGGTTAGTGCA
TGAATATGACGATATAGACCCAAATCAAGTTTTCAAAGCAATTAGTTTTGCTTTACAGCAATACCCACTTTATGTTAGAC
AAATCAACTCTTATTTGATTTCATTGGAAGAAGACAATGGCTATAAAAAGTAA

Antitoxin

Protein

• Length: 151 a.a.
• Molecular weight: 17493.12 Da
• Isoelectric Point: 6.4818

>AT75927 WP_190602323.1 NZ_CP021056:3945799-3946251 [Richelia sinica FACHB-800]
MQKDTPTITELKQLSLQLPEKIPYLKMLVLFGSRATGNTKANSDWDFAVLCDEEQRQTYIGNHHSSLFELPSLVGQLLKI
NSDIIDIVELNHCSWLIAHFIARDGIVLFEKYCGEFEKFKLNSLKSETELKQYRQEQYRILDRELKKWGA

Nucleotide

• Length: 453 bp

>AT75927 NZ_CP021056:3945799-3946251 [Richelia sinica FACHB-800]
ATGCAAAAAGACACTCCCACAATTACAGAACTTAAACAACTATCCTTACAACTGCCAGAAAAAATACCTTACTTGAAAAT
GTTAGTTCTCTTTGGTTCTAGAGCAACTGGTAATACCAAAGCTAATAGTGACTGGGATTTTGCAGTTTTATGTGACGAAG
AACAACGTCAGACTTACATAGGAAATCATCATTCTTCTTTATTTGAACTACCAAGTTTGGTTGGGCAATTGTTAAAAATA
AATTCTGACATTATAGATATTGTCGAACTCAATCATTGTTCTTGGTTAATTGCTCATTTTATAGCCCGTGATGGAATTGT
CTTGTTTGAAAAATATTGTGGAGAATTTGAGAAATTTAAATTAAATTCATTGAAAAGTGAAACTGAGTTAAAACAATATC
GCCAAGAACAATATCGAATCCTTGACAGAGAATTAAAGAAGTGGGGAGCATGA