Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3860501..3860723 Replicon chromosome
Accession NZ_CP020545
Organism Escherichia coli strain ZJ3920

Toxin (Protein)


Gene name ldrD Uniprot ID S1NWX0
Locus tag B6V57_RS20120 Protein ID WP_001295224.1
Coordinates 3860501..3860608 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3860665..3860723 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B6V57_RS20095 3855755..3856507 - 753 WP_148123950.1 cellulose biosynthesis protein BcsQ -
B6V57_RS20100 3856519..3856707 - 189 WP_001063314.1 YhjR family protein -
B6V57_RS20105 3856980..3858551 + 1572 WP_001204957.1 cellulose biosynthesis protein BcsE -
B6V57_RS20110 3858548..3858739 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
B6V57_RS20115 3858736..3860415 + 1680 WP_000191567.1 cellulose biosynthesis protein BcsG -
B6V57_RS20120 3860501..3860608 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- 3860665..3860723 + 59 - - Antitoxin
B6V57_RS28500 3860984..3861091 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
B6V57_RS20140 3861466..3861573 - 108 WP_000170745.1 type I toxin-antitoxin system toxin Ldr family protein -
B6V57_RS20150 3862049..3863320 + 1272 WP_001332306.1 amino acid permease -
B6V57_RS20155 3863350..3864354 - 1005 WP_148123951.1 dipeptide ABC transporter ATP-binding subunit DppF -
B6V57_RS20160 3864351..3865334 - 984 WP_001196477.1 dipeptide ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3882.70 Da        Isoelectric Point: 9.0157

>T75103 WP_001295224.1 NZ_CP020545:c3860608-3860501 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T75103 NZ_CP020545:c3860608-3860501 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 59 bp

>AT75103 NZ_CP020545:3860665-3860723 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TSJ7

Antitoxin

Download structure file

References