Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1988119..1988390 Replicon chromosome
Accession NZ_CP020543
Organism Escherichia coli C

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1988249..1988352 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1988119..1988390 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B6N50_RS10040 (B6N50_10040) 1984674..1985336 - 663 WP_000944258.1 exodeoxyribonuclease X -
B6N50_RS10045 (B6N50_10045) 1985360..1986016 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
B6N50_RS10050 (B6N50_10050) 1986118..1986348 - 231 WP_000916763.1 DNA polymerase III subunit theta -
B6N50_RS10055 (B6N50_10055) 1986487..1986861 + 375 WP_000168747.1 CopC domain-containing protein YobA -
B6N50_RS10060 (B6N50_10060) 1986865..1987737 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
B6N50_RS10065 (B6N50_10065) 1987750..1988091 + 342 WP_000976472.1 YebY family protein -
- 1988119..1988390 - 272 - - Antitoxin
- 1988249..1988352 + 104 - - Toxin
B6N50_RS10070 (B6N50_10070) 1988487..1989143 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
B6N50_RS10075 (B6N50_10075) 1989144..1989335 - 192 WP_001338167.1 YebW family protein -
B6N50_RS10080 (B6N50_10080) 1989440..1989676 - 237 WP_001338166.1 DUF1480 family protein -
B6N50_RS10085 (B6N50_10085) 1989794..1991233 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T75063 NZ_CP020543:1988249-1988352 [Escherichia coli C]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT75063 NZ_CP020543:c1988390-1988119 [Escherichia coli C]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References