Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2085552..2085692 Replicon chromosome
Accession NZ_CP020507
Organism Serratia marcescens strain BWH-35

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2085596..2085692 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2085552..2085692 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AS658_RS10160 2080753..2081178 + 426 WP_033653830.1 RNA polymerase-binding protein DksA -
AS658_RS10165 2081373..2082326 + 954 WP_038875880.1 prolyl aminopeptidase -
AS658_RS10170 2082360..2082590 - 231 WP_033638067.1 DNA polymerase III subunit theta -
AS658_RS10175 2082931..2083449 + 519 WP_038875847.1 non-heme ferritin -
AS658_RS10180 2083743..2084159 + 417 WP_048233438.1 CopC domain-containing protein YobA -
AS658_RS10185 2084162..2085043 + 882 WP_048233440.1 copper homeostasis membrane protein CopD -
AS658_RS10190 2085113..2085454 + 342 WP_025302452.1 YebY family protein -
- 2085552..2085692 - 141 - - Antitoxin
- 2085596..2085692 + 97 - - Toxin
AS658_RS10195 2086113..2086442 - 330 WP_038875697.1 DUF1493 family protein -
AS658_RS10200 2086436..2086894 - 459 WP_048233442.1 hypothetical protein -
AS658_RS10205 2087298..2087597 - 300 WP_181423508.1 hypothetical protein -
AS658_RS10215 2088267..2088617 + 351 WP_033638116.1 DUF4377 domain-containing protein -
AS658_RS10220 2088668..2088970 - 303 WP_038875692.1 hypothetical protein -
AS658_RS10225 2089257..2090456 + 1200 WP_047727768.1 trans-2-enoyl-CoA reductase family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T74847 NZ_CP020507:2085596-2085692 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT74847 NZ_CP020507:c2085692-2085552 [Serratia marcescens]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References