Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2549280..2549464 Replicon chromosome
Accession NZ_CP020467
Organism Staphylococcus aureus strain CFSAN007896

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag AB477_RS13235 Protein ID WP_000482647.1
Coordinates 2549357..2549464 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2549280..2549340 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB477_RS13210 2544790..2544957 - 168 Protein_2455 hypothetical protein -
AB477_RS13220 2545188..2546921 - 1734 WP_107375256.1 ABC transporter ATP-binding protein/permease -
AB477_RS13225 2546946..2548709 - 1764 WP_001064829.1 ABC transporter ATP-binding protein/permease -
- 2549280..2549340 + 61 - - Antitoxin
AB477_RS13235 2549357..2549464 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
AB477_RS13240 2549598..2549984 - 387 WP_000779351.1 flippase GtxA -
AB477_RS13245 2550252..2551394 + 1143 WP_001176855.1 glycerate kinase -
AB477_RS13250 2551454..2552113 + 660 WP_000831298.1 membrane protein -
AB477_RS13255 2552295..2553506 + 1212 WP_001191919.1 multidrug effflux MFS transporter -
AB477_RS13260 2553629..2554102 - 474 WP_000456496.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T74725 WP_000482647.1 NZ_CP020467:c2549464-2549357 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T74725 NZ_CP020467:c2549464-2549357 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT74725 NZ_CP020467:2549280-2549340 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References