Detailed information of TA system TA074703

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 4615459..4616003
• Replicon: chromosome
• Accession: NZ_CP020465
• Organism: Colwellia beringensis strain NB097-1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: B5D82_RS19510
• Protein ID: WP_081154142.1
• Coordinates: 4615459..4615758 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: B5D82_RS19515
• Protein ID: WP_081154143.1
• Coordinates: 4615746..4616003 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B5D82_RS19465	4610663..4611226	-	564	WP_081154123.1	hypothetical protein	-
B5D82_RS19470	4611290..4611577	-	288	WP_081154125.1	hypothetical protein	-
B5D82_RS19475	4611724..4612203	-	480	WP_081154128.1	thioesterase family protein	-
B5D82_RS19480	4612345..4612857	-	513	WP_081154130.1	hypothetical protein	-
B5D82_RS19485	4612948..4613736	-	789	WP_081154132.1	phytanoyl-CoA dioxygenase family protein	-
B5D82_RS19490	4613860..4614201	-	342	WP_081154134.1	hypothetical protein	-
B5D82_RS19495	4614316..4614501	-	186	WP_081154136.1	hypothetical protein	-
B5D82_RS19500	4614589..4614843	-	255	WP_081154138.1	hypothetical protein	-
B5D82_RS19505	4614957..4615337	-	381	WP_081154140.1	energy transducer TonB	-
B5D82_RS19510	4615459..4615758	-	300	WP_081154142.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
B5D82_RS19515	4615746..4616003	-	258	WP_081154143.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
B5D82_RS19520	4616158..4616451	-	294	Protein_3803	type II toxin-antitoxin system RelE/ParE family toxin	-
B5D82_RS19525	4616448..4616729	-	282	WP_081154145.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
B5D82_RS19530	4616917..4617918	-	1002	WP_157673943.1	DUF2314 domain-containing protein	-
B5D82_RS19975	4618423..4618560	-	138	WP_157673944.1	hypothetical protein	-
B5D82_RS19540	4618939..4619358	-	420	WP_081154148.1	hypothetical protein	-
B5D82_RS19545	4619400..4619924	-	525	WP_081154150.1	AAA family ATPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-89)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-63)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11612.48 Da
• Isoelectric Point: 6.9786

>T74703 WP_081154142.1 NZ_CP020465:c4615758-4615459 [Colwellia beringensis]
MAEVIWTSPALDDLNDVAEYIALSNLIAAQKLVQKVFDKVSRLESYPESGKRPAELINLNYREVIVNPCRIFYKTESDKV
YILHVMRQELDLRRFLLQR

Nucleotide

• Length: 300 bp

>T74703 NZ_CP020465:c4615758-4615459 [Colwellia beringensis]
ATGGCTGAAGTAATATGGACATCTCCAGCTCTTGATGATCTAAATGATGTTGCTGAATATATTGCTTTAAGTAATCTAAT
TGCGGCTCAAAAATTGGTACAAAAAGTATTTGATAAAGTATCAAGACTAGAAAGCTATCCAGAATCAGGTAAAAGACCTG
CTGAGCTAATTAACTTAAACTACCGAGAAGTTATTGTTAATCCGTGTCGTATTTTCTATAAAACTGAAAGTGACAAGGTT
TATATTTTACATGTAATGCGACAAGAGCTAGATTTACGCAGATTTCTTTTACAGCGTTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9701.24 Da
• Isoelectric Point: 7.3178

>AT74703 WP_081154143.1 NZ_CP020465:c4616003-4615746 [Colwellia beringensis]
MRVELVTTLKRQATKILADLHISKEPVLITEHGQPSAYLVDVDDYEFMQQRIAILEGVARGEQAIKNGHLLSNQEAKEKM
SKWLK

Nucleotide

• Length: 258 bp

>AT74703 NZ_CP020465:c4616003-4615746 [Colwellia beringensis]
ATGAGAGTTGAGCTAGTTACGACCCTTAAACGCCAAGCTACCAAAATATTAGCTGATCTTCACATTTCAAAAGAACCTGT
GTTAATTACTGAACATGGTCAACCATCTGCTTATTTAGTTGATGTTGATGATTATGAATTCATGCAACAACGAATAGCAA
TCCTTGAAGGTGTAGCTCGCGGTGAACAAGCTATTAAAAATGGCCATTTATTATCTAATCAAGAAGCCAAAGAGAAAATG
AGTAAATGGCTGAAGTAA