Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafN(antitoxin)
Location 1308165..1308730 Replicon chromosome
Accession NZ_CP020034
Organism Vibrio parahaemolyticus strain 20130629002S01

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag Vp2S01_RS06535 Protein ID WP_031856567.1
Coordinates 1308443..1308730 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag Vp2S01_RS06530 Protein ID WP_031856568.1
Coordinates 1308165..1308446 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Vp2S01_RS06485 1303289..1303876 + 588 WP_031856425.1 HD domain-containing protein -
Vp2S01_RS06490 1303890..1304363 + 474 WP_005458833.1 DUF2947 domain-containing protein -
Vp2S01_RS06495 1304414..1305376 - 963 WP_023623891.1 integron integrase -
Vp2S01_RS06500 1305633..1306133 + 501 WP_031856426.1 hypothetical protein -
Vp2S01_RS06505 1306172..1306264 + 93 WP_079880850.1 DUF3265 domain-containing protein -
Vp2S01_RS06510 1306292..1306822 + 531 WP_050505289.1 hypothetical protein -
Vp2S01_RS06515 1306985..1307308 - 324 WP_168192476.1 hypothetical protein -
Vp2S01_RS06520 1307395..1307526 + 132 WP_004418121.1 DUF3265 domain-containing protein -
Vp2S01_RS06530 1308165..1308446 + 282 WP_031856568.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
Vp2S01_RS06535 1308443..1308730 + 288 WP_031856567.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Vp2S01_RS06540 1308877..1309149 + 273 WP_031856534.1 nicotinamide mononucleotide transporter -
Vp2S01_RS27195 1309124..1309270 + 147 WP_108678091.1 DUF3265 domain-containing protein -
Vp2S01_RS27395 1309462..1309818 + 357 Protein_1122 DUF3265 domain-containing protein -
Vp2S01_RS06560 1309846..1310196 + 351 WP_025502458.1 hypothetical protein -
Vp2S01_RS06565 1310193..1310315 + 123 WP_071652165.1 DUF3265 domain-containing protein -
Vp2S01_RS06570 1310675..1310803 + 129 WP_108744602.1 DUF3265 domain-containing protein -
Vp2S01_RS06575 1311086..1311211 + 126 WP_085576728.1 DUF3265 domain-containing protein -
Vp2S01_RS06585 1312343..1313143 + 801 WP_043037961.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 1304414..1428522 124108


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-74)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10986.63 Da        Isoelectric Point: 4.6104

>T73824 WP_031856567.1 NZ_CP020034:1308443-1308730 [Vibrio parahaemolyticus]
MKVVWSPLALQKLGDAAEFISLDNPAAAENWINEVFDKTELLGSMPEMGRFVPEMPNTNYREIIFGHYRIIYSLSHEIRV
LTVRNCRQMLSEDDL

Download         Length: 288 bp

>T73824 NZ_CP020034:1308443-1308730 [Vibrio parahaemolyticus]
ATGAAAGTAGTTTGGTCTCCACTAGCGCTTCAGAAGCTAGGTGATGCAGCGGAATTTATTTCTTTGGATAATCCAGCTGC
AGCAGAAAACTGGATAAACGAAGTTTTTGACAAAACTGAACTACTTGGAAGTATGCCTGAAATGGGGCGCTTTGTTCCTG
AAATGCCCAATACTAACTATCGTGAAATCATTTTTGGTCACTATCGTATTATCTATAGCTTAAGCCATGAAATCCGAGTA
CTGACAGTTCGTAATTGCCGTCAAATGTTGTCGGAAGATGACCTGTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10428.93 Da        Isoelectric Point: 5.8650

>AT73824 WP_031856568.1 NZ_CP020034:1308165-1308446 [Vibrio parahaemolyticus]
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGISN
DDARSQVLGRIKK

Download         Length: 282 bp

>AT73824 NZ_CP020034:1308165-1308446 [Vibrio parahaemolyticus]
ATGAGCCGTATTCATTTCGATCAAGATATTCAGCCGTTATCTGAATTTCGCGCAGGTGTAGCTTCTTACATCAAACAAAT
CAACGAGACTCGCCGTCCATTGGTTATCACACAGCGTGGTAAAGGTGTAGCTGTTGTTCTCGATGTTGCAGAGTATGAAG
CAATGCAAGAGAAGATCGAGTTACTGGAAGAAATGCGCACAGCTGAAGCTCAATTAGCTTCAGGCCTTGGTATTTCAAAT
GATGATGCTCGTTCTCAAGTACTGGGGCGCATTAAGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References