Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 2421170..2421711 Replicon chromosome
Accession NZ_CP019875
Organism Komagataeibacter nataicola strain RZS01

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag B0W47_RS11630 Protein ID WP_078526248.1
Coordinates 2421170..2421469 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag B0W47_RS11635 Protein ID WP_078526250.1
Coordinates 2421469..2421711 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B0W47_RS11605 2416366..2416647 - 282 WP_078528003.1 transposase -
B0W47_RS11610 2416535..2417293 + 759 Protein_2296 IS5 family transposase -
B0W47_RS11615 2417357..2418700 + 1344 WP_075595799.1 IS1182 family transposase -
B0W47_RS11620 2418810..2420153 + 1344 WP_075595799.1 IS1182 family transposase -
B0W47_RS11625 2420266..2421044 + 779 WP_205836688.1 IS5 family transposase -
B0W47_RS11630 2421170..2421469 - 300 WP_078526248.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
B0W47_RS11635 2421469..2421711 - 243 WP_078526250.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
B0W47_RS11645 2422308..2423678 + 1371 WP_078526252.1 hypothetical protein -
B0W47_RS11650 2423756..2424476 - 721 Protein_2303 IS5 family transposase -
B0W47_RS11655 2424744..2425424 + 681 WP_078526254.1 DNA methylase -
B0W47_RS11665 2426034..2426519 + 486 WP_078526258.1 DUF2285 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2409669..2426519 16850
- inside IScluster/Tn - - 2416601..2428221 11620


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11498.04 Da        Isoelectric Point: 6.4775

>T73410 WP_078526248.1 NZ_CP019875:c2421469-2421170 [Komagataeibacter nataicola]
MRFLLRPAAQADLSAIWDYSAQQWGTTQADDYVRAIGRVCHDLADGTRHGRTADDIREGYLKMLVGSHLLFFRVNEDGFI
DVIRILHERMDPRRYMTDV

Download         Length: 300 bp

>T73410 NZ_CP019875:c2421469-2421170 [Komagataeibacter nataicola]
ATGCGTTTTCTTTTAAGGCCAGCGGCCCAAGCCGATCTGTCAGCAATCTGGGATTATTCAGCACAACAATGGGGAACCAC
TCAGGCCGACGACTATGTTCGAGCTATTGGGCGAGTCTGTCACGATCTCGCGGACGGAACACGACATGGACGGACTGCCG
ACGATATTCGGGAAGGGTATCTCAAGATGCTCGTCGGCTCTCATCTGTTGTTTTTTCGAGTTAACGAGGATGGCTTTATC
GACGTAATCCGTATCCTGCACGAGCGTATGGACCCCAGACGCTATATGACAGATGTGTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8903.86 Da        Isoelectric Point: 4.5859

>AT73410 WP_078526250.1 NZ_CP019875:c2421711-2421469 [Komagataeibacter nataicola]
MARNTSISLGDHFADFVDQQVQGGRYGSASDVIRAGLRILEERETRLETLRSALIDGEQSGAAEPFDIEDFLTTKAKQFR

Download         Length: 243 bp

>AT73410 NZ_CP019875:c2421711-2421469 [Komagataeibacter nataicola]
ATGGCGCGCAACACATCAATTTCACTCGGCGACCATTTCGCGGATTTCGTAGACCAGCAGGTGCAAGGTGGACGCTACGG
CTCGGCGAGCGACGTCATACGCGCTGGCCTGCGGATTCTTGAAGAGCGGGAGACACGACTTGAAACTCTTCGCTCCGCCC
TGATCGACGGCGAGCAGTCCGGTGCAGCCGAGCCGTTCGATATAGAAGATTTCCTCACCACGAAGGCTAAACAGTTCCGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References