Detailed information of TA system TA073202

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vagCD/VapC-VagC
• Location: 524926..525569
• Replicon: chromosome
• Accession: NZ_CP019706
• Organism: Pantoea alhagi strain LTYR-11Z

Toxin (Protein)

• Gene name: vagD
• Uniprot ID: -
• Locus tag: B1H58_RS02440
• Protein ID: WP_085067816.1
• Coordinates: 525153..525569 (+)
• Length: 139 a.a.

Antitoxin (Protein)

• Gene name: vagC
• Uniprot ID: -
• Locus tag: B1H58_RS02435
• Protein ID: WP_085067815.1
• Coordinates: 524926..525156 (+)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B1H58_RS02415	520162..521547	-	1386	WP_085067812.1	diaminobutyrate--2-oxoglutarate transaminase	-
B1H58_RS02420	522175..523536	+	1362	WP_085067813.1	lysine-sensitive aspartokinase 3	-
B1H58_RS02425	523764..524258	-	495	WP_085067814.1	DUF523 domain-containing protein	-
B1H58_RS02430	524338..524625	-	288	WP_157130137.1	RidA family protein	-
B1H58_RS02435	524926..525156	+	231	WP_085067815.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
B1H58_RS02440	525153..525569	+	417	WP_085067816.1	type II toxin-antitoxin system VapC family toxin	Toxin
B1H58_RS02450	526199..527356	+	1158	Protein_474	IS3 family transposase	-
B1H58_RS02455	527526..528637	+	1112	WP_157130138.1	IS3 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (5-129)

Antitoxin

• SpoVT-AbrB domain (7-50)

Sequences

Toxin

Protein

• Length: 139 a.a.
• Molecular weight: 15087.61 Da
• Isoelectric Point: 8.7652

>T73202 WP_085067816.1 NZ_CP019706:525153-525569 [Pantoea alhagi]
MNKIYMLDTCICSFIMREQPEAVLKRLEQAVLRSQRIVVSAITYAEMRFGATGPKASPRHIQLVDAFCARLDAILPWDRA
AVDATTGIRVALRLAGTPIGPNDTAIAGHAIATGAVLVTNNVREFARVPGLTLEDWVR

Nucleotide

• Length: 417 bp

>T73202 NZ_CP019706:525153-525569 [Pantoea alhagi]
ATGAACAAGATTTATATGCTCGATACCTGTATCTGCTCGTTCATTATGCGTGAGCAGCCGGAAGCCGTACTTAAGCGCCT
GGAGCAGGCGGTGCTGCGCAGCCAGCGCATCGTGGTATCGGCCATTACCTACGCCGAAATGCGCTTCGGCGCCACTGGCC
CGAAGGCCTCGCCACGCCACATCCAGTTGGTCGATGCATTCTGCGCCCGCCTCGATGCCATCCTGCCCTGGGACCGCGCT
GCGGTGGACGCCACCACGGGCATCCGGGTCGCGCTGCGGCTGGCCGGTACGCCGATAGGCCCGAACGACACGGCGATTGC
CGGGCATGCCATCGCCACCGGCGCCGTACTGGTCACGAATAATGTGCGGGAGTTTGCGCGGGTGCCGGGGCTGACACTGG
AAGACTGGGTTCGCTGA

Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 8723.80 Da
• Isoelectric Point: 4.3654

>AT73202 WP_085067815.1 NZ_CP019706:524926-525156 [Pantoea alhagi]
MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIVREGDSIILRPVRPTWGSFAQLEKADPDFMAEREDVVSDEGRFDL

Nucleotide

• Length: 231 bp

>AT73202 NZ_CP019706:524926-525156 [Pantoea alhagi]
ATGAGAACCGTATCCATTTTCAAAAATGGCAACAACCGCGCCATCCGTCTGCCCCGAGATCTGGATTTTGAGGGAGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATCATCCTGCGTCCCGTCCGGCCGACCTGGGGCTCGTTCGCGCAGCTGG
AAAAGGCCGATCCGGACTTTATGGCGGAGCGTGAGGACGTTGTCAGCGACGAAGGACGTTTTGATTTATGA