Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 3436144..3436744 Replicon chromosome
Accession NZ_CP019607
Organism Tessaracoccus flavescens strain SST-39T

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag BW733_RS16580 Protein ID WP_077352264.1
Coordinates 3436430..3436744 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BW733_RS16575 Protein ID WP_077352263.1
Coordinates 3436144..3436437 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BW733_RS16550 3432277..3432594 + 318 WP_077352255.1 hypothetical protein -
BW733_RS16555 3432742..3433695 + 954 WP_077352257.1 FKBP-type peptidyl-prolyl cis-trans isomerase -
BW733_RS16560 3433991..3434467 - 477 WP_202970235.1 GNAT family N-acetyltransferase -
BW733_RS18055 3434490..3434729 + 240 WP_152024770.1 hypothetical protein -
BW733_RS16565 3434889..3435476 + 588 WP_202970236.1 dihydrofolate reductase family protein -
BW733_RS16570 3435552..3435989 - 438 WP_077352261.1 FadR family transcriptional regulator -
BW733_RS16575 3436144..3436437 - 294 WP_077352263.1 putative addiction module antidote protein Antitoxin
BW733_RS16580 3436430..3436744 - 315 WP_077352264.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BW733_RS16585 3436851..3438482 + 1632 WP_077346978.1 IS1182 family transposase -
BW733_RS16590 3438750..3439433 - 684 WP_152024771.1 hypothetical protein -
BW733_RS16595 3439775..3441406 + 1632 WP_077346978.1 IS1182 family transposase -
BW733_RS16600 3441601..3441720 - 120 WP_077353098.1 GntR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-96)

Antitoxin

Uncharacterized protein HI1420

(6-96)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11856.51 Da        Isoelectric Point: 8.0393

>T72813 WP_077352264.1 NZ_CP019607:c3436744-3436430 [Tessaracoccus flavescens]
VIEVLTTQEFDHWLRRLKDRQGRLRILSRLDRLAAGNLGDMKPVGGGVLELRLAFGPGYRVYLTRRGHQLVLLLCGGDKS
SQSDDIIRARQLAAEWNEKEDNDE

Download         Length: 315 bp

>T72813 NZ_CP019607:c3436744-3436430 [Tessaracoccus flavescens]
GTGATCGAGGTTCTCACGACCCAGGAGTTCGATCACTGGCTGCGTCGGCTCAAGGATCGCCAGGGCCGCTTGCGGATCTT
GTCGAGACTCGACCGCCTTGCAGCAGGGAACCTCGGAGACATGAAACCCGTGGGTGGTGGGGTCCTGGAGCTTCGTCTGG
CGTTCGGTCCCGGCTACCGCGTCTACCTCACGCGGCGTGGCCACCAGCTGGTGCTGTTGCTGTGCGGTGGGGACAAGTCC
AGTCAGTCTGACGACATCATCAGGGCTCGTCAGCTGGCGGCCGAGTGGAACGAGAAGGAGGACAACGATGAGTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10384.61 Da        Isoelectric Point: 4.5086

>AT72813 WP_077352263.1 NZ_CP019607:c3436437-3436144 [Tessaracoccus flavescens]
MSENHQRFDAANYLDDLDDVAGYLQIALEESGDDPTAVPRALGVIARSGNMSELARRVGMSRDGLYKALSDQGNPTWSTV
LKVSGALGLKLSFQAVA

Download         Length: 294 bp

>AT72813 NZ_CP019607:c3436437-3436144 [Tessaracoccus flavescens]
ATGAGTGAGAACCATCAGCGCTTTGACGCCGCGAACTACCTCGACGACCTCGACGACGTCGCCGGCTACCTGCAGATCGC
CCTCGAGGAGTCCGGCGACGACCCAACTGCCGTTCCGCGCGCTCTCGGGGTGATCGCCCGCTCGGGGAACATGAGCGAAC
TCGCCCGCCGTGTCGGCATGAGCCGGGATGGGCTCTACAAGGCCCTGTCCGACCAGGGCAATCCCACGTGGTCGACCGTG
CTGAAGGTCAGCGGAGCGCTGGGCCTGAAGCTGTCCTTCCAGGCCGTCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References