Detailed information of TA system TA072410

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/-
• Location: 4480487..4481141
• Replicon: chromosome
• Accession: NZ_CP019399
• Organism: Pseudomonas chlororaphis strain R47

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: PchlR47_RS19735
• Protein ID: WP_159299225.1
• Coordinates: 4480487..4480837 (+)
• Length: 117 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: PchlR47_RS19740
• Protein ID: WP_009049793.1
• Coordinates: 4480827..4481141 (+)
• Length: 105 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PchlR47_RS19725	4477237..4478769	+	1533	WP_124301865.1	NADH-quinone oxidoreductase subunit M	-
PchlR47_RS19730	4478777..4480240	+	1464	WP_009049791.1	NADH-quinone oxidoreductase subunit NuoN	-
PchlR47_RS19735	4480487..4480837	+	351	WP_159299225.1	toxin	Toxin
PchlR47_RS19740	4480827..4481141	+	315	WP_009049793.1	transcriptional regulator	Antitoxin
PchlR47_RS19745	4481308..4483050	-	1743	WP_023964376.1	ABC transporter substrate-binding protein	-
PchlR47_RS19750	4483214..4483486	-	273	WP_009049795.1	DUF2160 domain-containing protein	-
PchlR47_RS19755	4483497..4484297	-	801	WP_007929618.1	carbohydrate ABC transporter permease	-
PchlR47_RS19760	4484309..4485175	-	867	WP_016701903.1	sugar ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Cro/C1-type helix-turn-helix domain (41-100)

Sequences

Toxin

Protein

• Length: 117 a.a.
• Molecular weight: 13831.82 Da
• Isoelectric Point: 9.4187

>T72410 WP_159299225.1 NZ_CP019399:4480487-4480837 [Pseudomonas chlororaphis]
MDALFIELPPFQRHRQDYLDDELFRSLQLELLKAPEVGDLIEGTGGLRKIRFVDERRHKGKRGGIRVIYYWWSGGAQFWL
FTLYAKNEQNDLTPHQKKLLKQLLNREVEARTHHET

Nucleotide

• Length: 351 bp

>T72410 NZ_CP019399:4480487-4480837 [Pseudomonas chlororaphis]
ATGGACGCACTTTTTATTGAGCTGCCCCCGTTCCAACGCCATCGACAGGACTACCTGGACGACGAGCTTTTTCGTAGCTT
GCAGCTTGAGTTGCTGAAAGCCCCCGAAGTCGGAGATCTCATCGAGGGAACAGGTGGCTTGCGCAAGATCCGCTTTGTCG
ATGAGCGACGGCACAAGGGCAAACGCGGCGGGATCCGGGTGATTTATTACTGGTGGTCCGGAGGCGCCCAATTCTGGCTC
TTCACCCTTTACGCAAAGAACGAGCAGAACGACCTGACACCCCATCAGAAAAAACTGCTCAAGCAACTGCTCAACAGAGA
AGTCGAGGCGAGAACCCATCATGAAACGTGA

Antitoxin

Protein

• Length: 105 a.a.
• Molecular weight: 11917.85 Da
• Isoelectric Point: 10.6052

>AT72410 WP_009049793.1 NZ_CP019399:4480827-4481141 [Pseudomonas chlororaphis]
MKRDIFSELVEGFDALAKERQGKLTLRTYKVKLNALLPITAEEVLAVREQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQATTLIRLVQRFPDTVERLAALA

Nucleotide

• Length: 315 bp

>AT72410 NZ_CP019399:4480827-4481141 [Pseudomonas chlororaphis]
ATGAAACGTGACATCTTTTCCGAACTGGTCGAAGGTTTCGACGCCCTGGCCAAAGAGCGCCAAGGCAAGCTCACGCTGCG
CACCTACAAGGTCAAGCTGAACGCGCTGCTCCCGATCACCGCTGAAGAAGTGCTGGCCGTACGCGAGCAGTTGAACCTGT
CCAGATCGGTATTTGCCATGTACCTGCGCACCAATACTCGGACCCTGGAGAACTGGGAGCAAGGACGGGCAAAACCCAAC
GCTCAGGCCACTACCCTGATCCGCCTGGTACAGCGTTTTCCCGATACGGTGGAGCGGCTGGCAGCATTGGCCTGA