Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3894082..3894304 Replicon chromosome
Accession NZ_CP019273
Organism Escherichia coli strain 13P477T

Toxin (Protein)


Gene name ldrD Uniprot ID S1NWX0
Locus tag BWI89_RS29345 Protein ID WP_001295224.1
Coordinates 3894197..3894304 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3894082..3894148 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BWI89_RS20135 3889470..3890453 + 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
BWI89_RS20140 3890450..3891454 + 1005 WP_000107036.1 dipeptide ABC transporter ATP-binding subunit DppF -
BWI89_RS20145 3891484..3892755 - 1272 WP_001318103.1 amino acid permease -
BWI89_RS29340 3893231..3893338 + 108 WP_000170738.1 type I toxin-antitoxin system toxin Ldr family protein -
BWI89_RS20165 3893714..3893821 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
- 3894082..3894148 - 67 - - Antitoxin
BWI89_RS29345 3894197..3894304 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
BWI89_RS29350 3894680..3894787 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
BWI89_RS20185 3894874..3896553 - 1680 WP_001562264.1 cellulose biosynthesis protein BcsG -
BWI89_RS20190 3896550..3896741 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
BWI89_RS20195 3896738..3898309 - 1572 WP_001204944.1 cellulose biosynthesis protein BcsE -
BWI89_RS20200 3898582..3898770 + 189 WP_001063315.1 YhjR family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3882.70 Da        Isoelectric Point: 9.0157

>T72163 WP_001295224.1 NZ_CP019273:3894197-3894304 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T72163 NZ_CP019273:3894197-3894304 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGCATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT72163 NZ_CP019273:c3894148-3894082 [Escherichia coli]
GTCTAGATGCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TSJ7

Antitoxin

Download structure file

References